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Int J Sports Med 2015; 36(02): 107-112
DOI: 10.1055/s-0034-1387762
Physiology & Biochemistry
© Georg Thieme Verlag KG Stuttgart · New York

Caffeinated Nitric Oxide-releasing Lozenge Improves Cycling Time Trial Performance

J. Lee
1   Kinesiology and Health Education, University of Texas at Austin, Austin, United States
,
H. T. Kim
1   Kinesiology and Health Education, University of Texas at Austin, Austin, United States
,
G. J. Solares
1   Kinesiology and Health Education, University of Texas at Austin, Austin, United States
,
K. Kim
1   Kinesiology and Health Education, University of Texas at Austin, Austin, United States
,
Z. Ding
1   Kinesiology and Health Education, University of Texas at Austin, Austin, United States
,
J. L. Ivy
1   Kinesiology and Health Education, University of Texas at Austin, Austin, United States
› Author Affiliations
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Publication History



accepted after revision 25 June 2014

Publication Date:
06 October 2014 (online)

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Abstract

Boosting nitric oxide production during exercise by various means has been found to improve exercise performance. We investigated the effects of a nitric oxide releasing lozenge with added caffeine (70 mg) on oxygen consumption during steady-state exercise and cycling time trial performance using a double-blinded randomized, crossover experimental design. 15 moderately trained cyclists (7 females and 8 males) were randomly assigned to ingest the caffeinated nitric oxide lozenge or placebo 5 min before exercise. Oxygen consumption and blood lactate were assessed at rest and at 50%, 65% and 75% maximal oxygen consumption. Exercise performance was assessed by time to complete a simulated 20.15 km cycling time-trial course. No significant treatment effects for oxygen consumption or blood lactate at rest or during steady-state exercise were observed. However, time-trial performance was improved by 2.1% (p<0.01) when participants consumed the nitric oxide lozenge (2 424±69 s) compared to placebo (2 476±78 s) and without a significant difference in rating of perceived exertion. These results suggest that acute supplementation with a caffeinated nitric oxide releasing lozenge may be a practical and effective means of improving aerobic exercise performance.

Key words

beetroot juice - nitrate - oxygen efficiency - nitrite - steady-state exercise
 

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