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DOI: 10.1055/s-0034-1395985
Outcome after Surgery for Acute Aortic Dissection Type A in the Elderly: A Single-Center Experience
Publikationsverlauf
07. August 2014
02. Oktober 2014
Publikationsdatum:
08. Januar 2015 (online)
Abstract
Objectives Despite improvements in surgical and perfusion techniques, surgery for acute aortic dissection type A (AADA) remains associated with high mortality rates. The aim of this study was to evaluate outcome after surgery for AADA in elderly in comparison with the outcome in younger patients.
Methods Between January 2004 and December 2012, 204 patients underwent operation for AADA. Of these, 65 patients were aged 70 years and older (elderly group; range, 70–85 years) and 139 were younger than 70 years (younger group; range, 18–69 years).
Results No significant differences were detected between the groups with regard to preoperative risk factors on admission. Significantly more number of elderly patients than younger underwent supracoronary replacement of the ascending aorta (93.8% versus 80.6%, p = 0.013). In comparison to the elderly patients, younger patients more frequently received complex surgery (Bentall and David operation). The mean extracorporeal circulation time (183 ± 62 minutes versus 158 ± 3 minutes; p = 0.003) and the mean aortic cross-clamp time (100 ± 45 minute versus 82 ± 30 minute; p = 0.006) were significantly higher for younger patients. No significant differences in postoperative complications and major morbidity were observed. The operative mortality (elderly group 4.6% versus younger group 1.4%; p = 0.33) and 30-day mortality (elderly group 18.5% versus younger group 8.6%; p = 0.06) were without statistical significance between the groups.
Conclusion Surgery for AADA in the elderly resulted in acceptable mortality. Satisfactory outcomes should encourage the offering of surgery in these patients.
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References
- 1 Mehta RH, Suzuki T, Hagan PG , et al; International Registry of Acute Aortic Dissection (IRAD) Investigators. Predicting death in patients with acute type A aortic dissection. Circulation 2002; 105 (2) 200-206
- 2 Trimarchi S, Eagle KA, Nienaber CA , et al; International Registry of Acute Aortic Dissection Investigators. Role of age in acute type A aortic dissection outcome: report from the International Registry of Acute Aortic Dissection (IRAD). J Thorac Cardiovasc Surg 2010; 140 (4) 784-789
- 3 Conzelmann LO, Krüger T, Hoffmann I , et al; Teilnehmenden GERAADA-Zentren. German Registry for Acute Aortic Dissection Type A (GERAADA): initial results [in German]. Herz 2011; 36 (6) 513-524
- 4 Rylski B, Suedkamp M, Beyersdorf F , et al. Outcome after surgery for acute aortic dissection type A in patients over 70 years: data analysis from the German Registry for Acute Aortic Dissection Type A (GERAADA). Eur J Cardiothorac Surg 2011; 40 (2) 435-440
- 5 Shiono M, Hata M, Sezai A, Iida M, Yagi S, Negishi N. Emergency surgery for acute type A aortic dissection in octogenarians. Ann Thorac Surg 2006; 82 (2) 554-559
- 6 Hata M, Sezai A, Niino T , et al. Should emergency surgical intervention be performed for an octogenarian with type A acute aortic dissection?. J Thorac Cardiovasc Surg 2008; 135 (5) 1042-1046
- 7 Piccardo A, Regesta T, Zannis K , et al. Outcomes after surgical treatment for type A acute aortic dissection in octogenarians: a multicenter study. Ann Thorac Surg 2009; 88 (2) 491-497
- 8 Tang GH, Malekan R, Yu CJ, Kai M, Lansman SL, Spielvogel D. Surgery for acute type A aortic dissection in octogenarians is justified. J Thorac Cardiovasc Surg 2013; 145 (3, Suppl): S186-S190
- 9 Evangelista A, Mukherjee D, Mehta RH , et al; International Registry of Aortic Dissection (IRAD) Investigators. Acute intramural hematoma of the aorta: a mystery in evolution. Circulation 2005; 111 (8) 1063-1070
- 10 Haneya A, Jussli-Melchers J, Berndt R , et al. Outcome and quality of life following surgery for acute type A aortic dissection in the elderly: A single center experience. 43. Jahrestagung der Deutschen Gesellschaft für Thorax-, Herz- und Gefächirurgie 2014; 62 (Suppl. 01) OP 82
- 11 Schoeneich F, Rahimi A, Hoffmann G, Eide M, Schöttler J, Cremer J. Transatrial left-ventricular cannulation in acute typ A aortic dissection: Save, easy and effective! 40. Jahrestagung der Deutschen Gesellschaft für Thorax-, Herz- und Gefächirurgie 2011; 59 (Suppl. 01) MO 66
- 12 Suzuki S, Masuda M. An update on surgery for acute type A aortic dissection: aortic root repair, endovascular stent graft, and genetic research. Surg Today 2009; 39 (4) 281-289
- 13 Matsushita A, Tabata M, Fukui T , et al. Outcomes of contemporary emergency open surgery for type A acute aortic dissection in elderly patients. J Thorac Cardiovasc Surg 2014; 147 (1) 290-294
- 14 Huber CH, Goeber V, Berdat P, Carrel T, Eckstein F. Benefits of cardiac surgery in octogenarians—a postoperative quality of life assessment. Eur J Cardiothorac Surg 2007; 31 (6) 1099-1105
- 15 Trimarchi S, Nienaber CA, Rampoldi V , et al; International Registry of Acute Aortic Dissection Investigators. Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experience. J Thorac Cardiovasc Surg 2005; 129 (1) 112-122
- 16 Stamou SC, Hagberg RC, Khabbaz KR , et al. Is advanced age a contraindication for emergent repair of acute type A aortic dissection?. Interact Cardiovasc Thorac Surg 2010; 10 (4) 539-544
- 17 Santini F, Montalbano G, Messina A , et al. Survival and quality of life after repair of acute type A aortic dissection in patients aged 75 years and older justify intervention. Eur J Cardiothorac Surg 2006; 29 (3) 386-391
- 18 Hata M, Suzuki M, Sezai A , et al. Less invasive quick replacement for octogenarians with type A acute aortic dissection. J Thorac Cardiovasc Surg 2008; 136 (2) 489-493
- 19 Hata M, Suzuki M, Sezai A , et al. Outcome of less invasive proximal arch replacement with moderate hypothermic circulatory arrest followed by aggressive rapid re-warming in emergency surgery for type A acute aortic dissection. Circ J 2009; 73 (1) 69-72
- 20 Czerny M, Fleck T, Zimpfer D , et al. Risk factors of mortality and permanent neurologic injury in patients undergoing ascending aortic and arch repair. J Thorac Cardiovasc Surg 2003; 126 (5) 1296-1301
- 21 Salis S, Mazzanti VV, Merli G , et al. Cardiopulmonary bypass duration is an independent predictor of morbidity and mortality after cardiac surgery. J Cardiothorac Vasc Anesth 2008; 22 (6) 814-822
- 22 Neri E, Toscano T, Massetti M , et al. Operation for acute type A aortic dissection in octogenarians: is it justified?. J Thorac Cardiovasc Surg 2001; 121 (2) 259-267