Thorac Cardiovasc Surg 2016; 64(02): 091-099
DOI: 10.1055/s-0035-1548734
Original Cardiovascular
Georg Thieme Verlag KG Stuttgart · New York

Long-Term Outcome and Quality of Life in Aortic Type A Dissection Survivors

Matthias Endlich
1   Department of Cardiovascular Surgery, University Hospital Bonn, Bonn, Germany
,
Marwan Hamiko
1   Department of Cardiovascular Surgery, University Hospital Bonn, Bonn, Germany
,
Christopher Gestrich
1   Department of Cardiovascular Surgery, University Hospital Bonn, Bonn, Germany
,
Chris Probst
1   Department of Cardiovascular Surgery, University Hospital Bonn, Bonn, Germany
,
Fritz Mellert
1   Department of Cardiovascular Surgery, University Hospital Bonn, Bonn, Germany
,
Kai Winkler
1   Department of Cardiovascular Surgery, University Hospital Bonn, Bonn, Germany
,
Armin Welz
1   Department of Cardiovascular Surgery, University Hospital Bonn, Bonn, Germany
,
Wolfgang Schiller
1   Department of Cardiovascular Surgery, University Hospital Bonn, Bonn, Germany
› Author Affiliations
Further Information

Publication History

18 November 2014

30 January 2015

Publication Date:
10 April 2015 (online)

Abstract

Background Aortic dissection is a severe and sophisticated disease that is often linked with a number of possible complications. Our study concerns with long-term outcome and quality of life (QoL) in acute aortic dissection type A (AADA) survivors.

Methods From January 1999 until December 2006, 120 consecutive patients with AADA received an emergency operation. Of the total number of patients, 84 were males (70.0%) and 36 females (30.0%), mean aged 59.8 ± 12 years with a mean follow-up (FU) of 99.2 ± 6 months.

Results Overall mortality was 39.1% during the observational period with a maximum of 156 months. SF-36 observation showed a significant decay in both Physical Component Summary (PCS) and Mental Component Summary (MCS) in FUII (PCS = 38.4) versus FUI (PCS = 43.4, p = 0.013).

Conclusion With ongoing postoperative time, patients did not recover but instead have got worse in terms of QoL. The decrease in MCP and linked subscores is an underestimated factor in QoL and long-term outcome after AADA. This is especially true in younger patients, which are judged to compensate better than older patients.

Note

Parts of this article were presented at the annual meeting of the German Society for Thoracic and Cardiovascular Surgery. Date and venue of presentation: February 19, 2013, Messe Freiburg, 79108 Freiburg, Germany.


 
  • References

  • 1 Suzuki S, Masuda M. An update on surgery for acute type A aortic dissection: aortic root repair, endovascular stent graft, and genetic research. Surg Today 2009; 39 (4) 281-289
  • 2 Cook RC, Gao M, Macnab AJ, Fedoruk LM, Day N, Janusz MT. Aortic arch reconstruction: safety of moderate hypothermia and antegrade cerebral perfusion during systemic circulatory arrest. J Card Surg 2006; 21 (2) 158-164
  • 3 Suzuki S, Imoto K, Uchida K, Takanashi Y. Aortic root necrosis after surgical treatment using gelatin-resorcinol-formaldehyde (GRF) glue in patients with acute type A aortic dissection. Ann Thorac Cardiovasc Surg 2006; 12 (5) 333-340
  • 4 Weigang E, Nienaber CA, Rehders TC, Ince H, Vahl CF, Beyersdorf F. Management of patients with aortic dissection. Dtsch Arztebl Int 2008; 105 (38) 639-645
  • 5 Bullinger M. German translation and psychometric testing of the SF-36 Health Survey: preliminary results from the IQOLA Project. International Quality of Life Assessment. Soc Sci Med 1995; 41 (10) 1359-1366
  • 6 Ware Jr JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992; 30 (6) 473-483
  • 7 Wagner A, Gandek B, Aaronson N , et al. Cross-cultural comparisons of the content of the SF-36 translations across 10 countries: results from the International Quality of Life Assessment Project. J Clin Epidemiol 1998; 51 (11) 925-932
  • 8 Ellert U, Der Bellach BM. Der SF-36 im Bundes-Gesundheitssurvey—Beschreibung einer aktuellen Normstichprobe. Gesundheitswesen 61. Sonderheft 1999; 2: 184-190
  • 9 Conzelmann LO, Krüger T, Hoffmann I , et al; Teilnehmenden GERAADA-Zentren. German Registry for Acute Aortic Dissection Type A (GERAADA): initial results [in German]. Herz 2011; 36 (6) 513-524
  • 10 Kallenbach K, Beller CJ, Karck M. Strategien der arteriellen Kanülierung bei akuter Aortendissektion Typ A zum Anschluss der Herz-Lungen-Maschine. Zeitschrift für Herz-, Thorax- und Gefäßchirurgie 2012; 26 (1) 7-13
  • 11 Schurr UP, Emmert MY, Berdajs D , et al. Subclavian artery cannulation provides superior outcomes in patients with acute type-A dissection: long-term results of 290 consecutive patients. Swiss Med Wkly 2013; 143: w13858
  • 12 Tiwari KK, Murzi M, Bevilacqua S, Glauber M. Which cannulation (ascending aortic cannulation or peripheral arterial cannulation) is better for acute type A aortic dissection surgery?. Interact Cardiovasc Thorac Surg 2010; 10 (5) 797-802
  • 13 Nouraei SM, Nouraei SA, Sadashiva AK, Pillay T. Subclavian cannulation improves outcome of surgery for type A aortic dissection. Asian Cardiovasc Thorac Ann 2007; 15 (2) 118-122
  • 14 Conzelmann LO, Hoffmann I, Blettner M , et al; GERAADA Investigators. Analysis of risk factors for neurological dysfunction in patients with acute aortic dissection type A: data from the German Registry for Acute Aortic Dissection type A (GERAADA). Eur J Cardiothorac Surg 2012; 42 (3) 557-565
  • 15 Olsson C, Thelin S. Quality of life in survivors of thoracic aortic surgery. Ann Thorac Surg 1999; 67 (5) 1262-1267
  • 16 Stalder M, Staffelbach S, Immer FF , et al. Aortic root replacement does not affect outcome and quality of life. Ann Thorac Surg 2007; 84 (3) 775-780 , discussion 780–781
  • 17 Lohse F, Lang N, Schiller W , et al. Quality of life after replacement of the ascending aorta in patients with true aneurysms. Tex Heart Inst J 2009; 36 (2) 104-110
  • 18 Campbell-Lloyd AJ, Mundy J, Pinto N , et al. Contemporary results following surgical repair of acute type A aortic dissection (AAAD): a single centre experience. Heart Lung Circ 2010; 19 (11) 665-672
  • 19 Kobuch R, Schelker E, Schmid C, Hirt S, Amann M, Diez C. Quality of life following surgery of ascending aorta and aortic arch with selective antegrade cerebral perfusion. Thorac Cardiovasc Surg 2012; 60 (8) 496-500
  • 20 Rowen D, Brazier J, Roberts J. Mapping SF-36 onto the EQ-5D index: how reliable is the relationship?. Health Qual Life Outcomes 2009; 7: 27
  • 21 Santini F, Montalbano G, Messina A , et al. Survival and quality of life after repair of acute type A aortic dissection in patients aged 75 years and older justify intervention. Eur J Cardiothorac Surg 2006; 29 (3) 386-391
  • 22 Küchler T, Bestmann B, Rappat S, Henne-Bruns D, Wood-Dauphinee S. Impact of psychotherapeutic support for patients with gastrointestinal cancer undergoing surgery: 10-year survival results of a randomized trial. J Clin Oncol 2007; 25 (19) 2702-2708
  • 23 Houle J, Doyon O, Vadeboncoeur N, Turbide G, Diaz A, Poirier P. Effectiveness of a pedometer-based program using a socio-cognitive intervention on physical activity and quality of life in a setting of cardiac rehabilitation. Can J Cardiol 2012; 28 (1) 27-32