Update on Prepregnancy Maternal Obesity: Birth Defects and Childhood Outcomes

Abstract

Obesity is a growing global health epidemic. It is estimated that more than 20% of pregnancies are complicated by obesity. Prepregnancy obesity has been associated with birth defects such as neural tube defects, macrosomia, fetal death, and long-term effects such as asthma on the offspring. We provide a summary of the most recent studies and meta-analyses on obesity and birth outcome. Possible mechanisms of actions are explored and recommendations for further research are highlighted.

Keywords

obesity - body mass index - pregnancy - major congenital malformations

• References

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