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J Pediatr Infect Dis 2007; 02(01): 051-054
DOI: 10.1055/s-0035-1557017
Case Report
Georg Thieme Verlag KG Stuttgart – New York

Pulmonary tuberculosis with meningitis in a 7-month-old infant

Ivana Goić-Barišić
a   Department of Clinical Microbiology, University Hospital Split and School of Medicine, University of Split, Split, Croatia
,
Neven Pavlov
b   Department of Pediatrics, University Hospital Split and School of Medicine, University of Split, Split, Croatia
,
Ivo Ivić
c   Department of Infectious Diseases, University Hospital Split, Split, Croatia
,
Marija Tonkić
a   Department of Clinical Microbiology, University Hospital Split and School of Medicine, University of Split, Split, Croatia
,
Igor Barišić
d   Department of Diagnostic and Interventional Radiology, University Hospital Split and School of Medicine, University of Split, Split, Croatia
,
Slavica Dragišić-Ivulić
b   Department of Pediatrics, University Hospital Split and School of Medicine, University of Split, Split, Croatia
,
Volga Punda-Polić
a   Department of Clinical Microbiology, University Hospital Split and School of Medicine, University of Split, Split, Croatia
› Author Affiliations
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Further Information

Publication History

25 August 2006

24 November 2006

Publication Date:
28 July 2015 (online)

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Abstract

Tuberculous meningitis is the most serious form of tuberculosis and carries a high mortality and morbidity despite the availability of effective chemotherapeutic agents. Poor response to therapy or death is often due to failure to begin appropriate therapy in the early stages of the disease. We report a rare case of tuberculous meningitis in a 7-month old infant following unsuccessful vaccination and close exposure to adult uncle who died from pulmonary tuberculosis when she was 3 months old. The described case points out serious possibility of pulmonary tuberculosis with meningitis in non-vaccinated or unsuccessfully vaccinated children and importance of the chemoprophylaxis in infants who were exposed to tuberculous infection, as well as early discovery and treatment of illness.

Keywords

Tuberculous meningitis - pulmonary tuberculosis - infant - BCG vaccination