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Journal of Pediatric Neurology 2004; 02(04): 219-223
DOI: 10.1055/s-0035-1557223
Original Article
Georg Thieme Verlag KG Stuttgart – New York

Absence of cytomegalovirus infection in children with acquired immunodeficiency syndrome and distal sensory polyneuropathy

Alexandra P. de Q. C. Araújo
1   Department of Pediatrics, The Federal University of Rio de Janeiro, Av Brigadeiro Trompowski S/N, Rio de Janeiro, Brazil
,
Suzie Couglan
2   National Virus Reference Laboratory, Medical Microbiology, University College Dublin, Belfield, Dublin 4, Ireland
,
William W. Hall
3   Department of Microbiology, University College Department of Dublin, Belfield, Dublin 4, Ireland
› Author Affiliations
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Publication History

06 April 2004

22 June 2004

Publication Date:
29 July 2015 (online)

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Abstract

To investigate the role of cytomegalovirus (CMV) infection in the pathogenesis of peripheral neuropathy in children with acquired immunodeficiency syndrome (AIDS) a cross-sectional descriptive study was conducted on a sample of nine children. Plasma samples were tested for CMV DNA by two polymerase chain reaction assays (sensitivity limits of 400 and 10 copies/mls) respectively. While all nine were CMV seropositive all were negative for viremia in both assays. CMV would appear not to be involved in children with AIDS-associated sensory neuropathies. (J Pediatr Neurol 2004; 2(4): 219–223).

Keywords

cytomegalovirus - peripheral nervous system disease - child - HIV