Download PDF
Int J Sports Med 2016; 37(02): 97-103
DOI: 10.1055/s-0035-1559791
Physiology & Biochemistry
© Georg Thieme Verlag KG Stuttgart · New York

Interrupting Sitting Time with Regular Walks Attenuates Postprandial Triglycerides

M. Miyashita
1   Department of Health and Sports Sciences, Tokyo Gakugei University, Koganei, Japan
,
K. Edamoto
1   Department of Health and Sports Sciences, Tokyo Gakugei University, Koganei, Japan
,
T. Kidokoro
1   Department of Health and Sports Sciences, Tokyo Gakugei University, Koganei, Japan
,
T. Yanaoka
1   Department of Health and Sports Sciences, Tokyo Gakugei University, Koganei, Japan
,
K. Kashiwabara
1   Department of Health and Sports Sciences, Tokyo Gakugei University, Koganei, Japan
,
M. Takahashi
2   Faculty of Science and Engineering, Waseda University, Shinjuku, Japan
,
S. Burns
3   Physical Education and Sports Science Academic Group, Nanyang Technological University, Singapore
› Author Affiliations
Further Information

Publication History



accepted after revision 07 August 2015

Publication Date:
28 October 2015 (online)

Also available at
    Permissions and Reprints

Abstract

We compared the effects of prolonged sitting with the effects of sitting interrupted by regular walking and the effects of prolonged sitting after continuous walking on postprandial triglyceride in postmenopausal women. 15 participants completed 3 trials in random order: 1) prolonged sitting, 2) regular walking, and 3) prolonged sitting preceded by continuous walking. During the sitting trial, participants rested for 8 h. For the walking trials, participants walked briskly in either twenty 90-sec bouts over 8 h or one 30-min bout in the morning (09:00–09:30). Except for walking, both exercise trials mimicked the sitting trial. In each trial, participants consumed a breakfast (08:00) and lunch (11:00). Blood samples were collected in the fasted state and at 2, 4, 6 and 8 h after breakfast. The serum triglyceride incremental area under the curve was 15 and 14% lower after regular walking compared with prolonged sitting and prolonged sitting after continuous walking (4.73±2.50 vs. 5.52±2.95 vs. 5.50±2.59 mmol/L∙8 h respectively, main effect of trial: P=0.023). Regularly interrupting sitting time with brief bouts of physical activity can reduce postprandial triglyceride in postmenopausal women.

Key words

postprandial period - sedentary lifestyle - short bouts of walking
 

  • References

  • 1 Altenburg TM, Rotteveel J, Dustan DW, Salmon J, Chinapaw MJ. The effect of interrupting prolonged sitting time with short, hourly, moderate-intensity cycling bouts on cardiometabolic risk factors in healthy, young adults. J Appl Physiol 2013; 115: 1751-1756
    CrossrefPubMedSearch in Google Scholar
  • 2 American College of Sports Medicine . Guidelines for Exercise Testing and Prescription. 8th (ed.) Philadelphia: Lippincott Williams and Wilkins; 2009: 158
    Search in Google Scholar
  • 3 Ando T, Usui C, Ohkawara K, Miyake R, Miyashita M, Park J, Ezaki O, Higuchi M, Tanaka S. Effects of intermittent physical activity on fat utilization over a whole day. Med Sci Sports Exerc 2013; 45: 1410-1418
    CrossrefPubMedSearch in Google Scholar
  • 4 Bailey DP, Locke CD. Breaking up prolonged sitting with light-intensity walking improves postprandial glycemia, but breaking up sitting with standing does not. J Sci Med Sport 2015; 18: 294-298
    CrossrefPubMedSearch in Google Scholar
  • 5 Bansal S, Buring JE, Rifai N, Mora S, Sacks FM, Ridker PM. Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 2007; 298: 309-316
    CrossrefPubMedSearch in Google Scholar
  • 6 Biswas A, Oh PI, Faulkner GE, Bajaj RR, Silver MA, Mitchell MS, Alter DA. Sedentary time and its association with risk for disease incidence, mortality, and hospitalization in adults: a systematic review and meta-analysis. Ann Intern Med 2015; 162: 123-132
    CrossrefPubMedSearch in Google Scholar
  • 7 Bey L, Hamilton MT. Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low-intensity activity. J Physiol 2003; 551: 673-682
    CrossrefPubMedSearch in Google Scholar
  • 8 Borg GA. Perceived exertion: a note on “history” and methods. Med Sci Sports 1973; 5: 90-93
    PubMedSearch in Google Scholar
  • 9 Castro Cabezas M, Halkes CJ, Meijssen S, van Oostrom AJ, Erkelens DW. Diurnal triglyceride profiles: a novel approach to study triglyceride changes. Atherosclerosis 2001; 155: 219-228
    CrossrefPubMedSearch in Google Scholar
  • 10 Dunstan DW, Barr EL, Healy GN, Salmon J, Shaw JE, Balkau B, Magliano DJ, Cameron AJ, Zimmet PZ, Owen N. Television viewing time and mortality: the Australian Diabetes, Obesity and Lifestyle Study (AusDiab). Circulation 2010; 121: 384-391
    CrossrefPubMedSearch in Google Scholar
  • 11 Dunstan DW, Kingwell BA, Larsen R, Healy GN, Cerin E, Hamilton MT, Shaw JE, Bertovic DA, Zimmet PZ, Salmon J, Owen N. Breaking up prolonged sitting reduces postprandial glucose and insulin responses. Diabetes Care 2012; 35: 976-983
    CrossrefPubMedSearch in Google Scholar
  • 12 Ferguson M, Alderson N, Trost S, Essig D. Effects of four different single exercise sessions on lipids, lipoproteins, and lipoprotein lipase. J Appl Physiol 1998; 85: 1169-174
    PubMedSearch in Google Scholar
  • 13 Ferreira AP, Ferreira CB, Brito CJ, Souza VC, Córdova C, Nóbrega OT, França NM. The effect of aerobic exercise intensity on attenuation of postprandial lipemia is dependent on apolipoprotein E genotype. Atherosclerosis 2013; 229: 139-144
    CrossrefPubMedSearch in Google Scholar
  • 14 Freese EC, Gist NH, Cureton KJ. Effect of prior exercise on postprandial lipemia: an updated quantitative review. J Appl Physiol 2014; 116: 67-75
    CrossrefPubMedSearch in Google Scholar
  • 15 Habas ME, Macdonald IA. Metabolic and cardiovascular responses to liquid and solid test meals. Br J Nutr 1998; 79: 241-247
    CrossrefPubMedSearch in Google Scholar
  • 16 Harriss DJ, Atkinson G. Ethical Standards in Sport and Exercise Science Research: 2014 Update. Int J Sports Med 2013; 34: 1025-1028
    Thieme ConnectPubMedSearch in Google Scholar
  • 17 Healy GN, Matthews CE, Dunstan DW, Winkler EA, Owen N. Sedentary time and cardio-metabolic biomarkers in US adults: NHANES 2003-2006. Eur Heart J 2011; 32: 590-597
    CrossrefPubMedSearch in Google Scholar
  • 18 Katzmarzyk PT, Church TS, Craig CL, Bouchard C. Sitting time and mortality from all causes, cardiovascular disease, and cancer. Med Sci Sports Exerc 2009; 41: 998-1005
    CrossrefPubMedSearch in Google Scholar
  • 19 Kumahara H, Schutz Y, Ayabe M, Yoshioka M, Yoshitake Y, Shindo M, Ishii K, Tanaka H. The use of uniaxial accelerometry for the assessment of physical-activity-related energy expenditure: a validation study against whole-body indirect calorimetry. Br J Nutr 2004; 91: 235-243
    CrossrefPubMedSearch in Google Scholar
  • 20 Larsen RN, Kingwell BA, Sethi P, Cerin E, Owen N, Dunstan DW. Breaking up prolonged sitting reduces resting blood pressure in overweight/obese adults. Nutr Metab Cardiovasc Dis 2014; 24: 976-982
    CrossrefPubMedSearch in Google Scholar
  • 21 Larsen RN, Kingwell BA, Robinson C, Hammond L, Cerin E, Shaw JE, Healy GN, Hamilton MT, Owen N, Dunstan DE. Breaking up of prolonged sitting over three days sustains, but does not enhance, lowering postprandial plasma glucose and insulin in overweight and obese adults. Clin Sci 2015; 129: 117-127
    CrossrefPubMedSearch in Google Scholar
  • 22 Latouche C, Jowett JB, Carey AL, Bertovic DA, Owen N, Dunstan DW, Kingwell BA. Effects of breaking up prolonged sitting on skeletal muscle gene expression. J Appl Physiol 2013; 114: 453-460
    CrossrefPubMedSearch in Google Scholar
  • 23 Maraki MI, Sidossis LS. The latest on the effect of prior exercise on postprandial lipaemia. Sports Med 2013; 43: 463-481
    CrossrefPubMedSearch in Google Scholar
  • 24 Marliss EB, Vranic M. Intense exercise has unique effects on both insulin release and its roles in glucoregulation: implications for diabetes. Diabetes 2002; 51 (Suppl. 01) S271-S283
    CrossrefPubMedSearch in Google Scholar
  • 25 Mekki N, Christofilis MA, Charbonnier M, Atlan-Gepner C, Defoort C, Juhel C, Borel P, Portugal H, Pauli AM, Vialettes B, Lairon D. Influence of obesity and body fat distribution on postprandial lipemia and triglyceride-rich lipoproteins in adult women. J Clin Endocrinol Metab 1999; 84: 184-191
    CrossrefPubMedSearch in Google Scholar
  • 26 Miyashita M, Burns SF, Stensel DJ. Accumulating short bouts of brisk walking reduces plasma triacylglycerol concentrations and resting blood pressure in healthy young men. Am J Clin Nutri 2008; 88: 1225-1231
    PubMedSearch in Google Scholar
  • 27 Miyashita M, Burns SF, Stensel DJ. Acute effects of accumulating exercise on postprandial lipemia and C-reactive protein concentrations in young men. Int J Sport Nutr Exerc Metab 2009; 19: 569-582
    PubMedSearch in Google Scholar
  • 28 Miyashita M, Burns SF, Stensel DJ. An update on accumulating exercise and postprandial lipaemia: translating theory into practice. J Prev Med Public Health 2013; 46: S3-S11
    CrossrefPubMedSearch in Google Scholar
  • 29 Miyashita M, Takahashi M, Burns S. Increased participation in weekend physical activity reduces postprandial lipemia in postmenopausal women. Int J Sports Med 2014; 35: 1059-1064
    Thieme ConnectPubMedSearch in Google Scholar
  • 30 Murphy MH, Nevill AM, Hardman AE. Different patterns of brisk walking are equally effective in decreasing postprandial lipaemia. Int J Obes Relat Metab Disord 2000; 24: 1303-1309
    CrossrefPubMedSearch in Google Scholar
  • 31 Nordestgaard BG, Benn M, Schnohr P, Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007; 298: 299-308
    CrossrefPubMedSearch in Google Scholar
  • 32 Nordestgaard BG, Varbo A. Triglycerides and cardiovascular disease. Lancet 2014; 384: 626-635
    CrossrefPubMedSearch in Google Scholar
  • 33 Peddie MC, Bone JL, Rehrer NJ, Skeaff CM, Gray AR, Perry TL. Breaking prolonged sitting reduces postprandial glycemia in healthy, normal-weight adults: a randomized crossover trial. Am J Clin Nutr 2013; 98: 358-366
    CrossrefPubMedSearch in Google Scholar
  • 34 Peddie MC, Rehrer NJ, Perry TL. Physical activity and postprandial lipidemia: are energy expenditure and lipoprotein lipase activity the real modulators of the positive effect?. Prog Lipid Res 2012; 51: 11-22
    CrossrefPubMedSearch in Google Scholar
  • 35 Seip RL, Mair K, Cole TG, Semenkovich CF. Induction of human skeletal muscle lipoprotein lipase gene expression by short-term exercise is transient. Am J Physiol 1997; 272: E255-E261
    PubMedSearch in Google Scholar
  • 36 Thackray AE, Barrett LA, Tolfrey K. Acute high-intensity interval running reduces postprandial lipemia in boys. Med Sci Sports Exerc 2013; 45: 1277-1284
    CrossrefPubMedSearch in Google Scholar
  • 37 Thorp AA, Kingwell BA, Sethi P, Hammond Owen N, Dunstan DW. Alternating bouts of sitting and standing attenuate postprandial glucose responses. Med Sci Sports Exerc 2014; 46: 2053-2061
    CrossrefPubMedSearch in Google Scholar
  • 38 Thosar SS, Bielko SL, Mather KJ, Johnston JD, Wallace JP. Effect of prolonged sitting and breaks in sitting time on endothelial function. Med Sci Sports Exerc 2015; 47: 843-849
    PubMedSearch in Google Scholar