Synthesis 2015; 47(21): 3257-3285
DOI: 10.1055/s-0035-1560344
review
© Georg Thieme Verlag Stuttgart · New York

Asymmetric Synthesis of Natural Products and Medicinal Drugs through One-Pot-Reaction Strategies

Bor-Cherng Hong*
Department of Chemistry and Biochemistry, National Chung Cheng University, Chiayi, 621, Taiwan   Email: chebch@ccu.edu.tw
,
Arun Raja
Department of Chemistry and Biochemistry, National Chung Cheng University, Chiayi, 621, Taiwan   Email: chebch@ccu.edu.tw
,
Vishal M. Sheth
Department of Chemistry and Biochemistry, National Chung Cheng University, Chiayi, 621, Taiwan   Email: chebch@ccu.edu.tw
› Author Affiliations
Further Information

Publication History

Received: 30 June 2015

Accepted after revision: 27 July 2015

Publication Date:
29 September 2015 (online)


Abstract

One-pot synthesis has become an important subject of modern synthetic chemistry owing to its efficiency, versatility and expediency in constructing complicated polycyclic ring systems, especially with a sustainable and catalytic aspect. This review aims to highlight the recent advances in this area with specific emphasis on the asymmetric synthesis of natural products and related core structures as well as medicinal drugs via one-pot operation.

1 Introduction

2 Double Reactions

3 Triple Reactions

4 Quadruple Reactions

5 Pot-Economy Reactions

6 Conclusions