Synthesis 2015; 47(23): 3629-3644
DOI: 10.1055/s-0035-1560356
review
© Georg Thieme Verlag Stuttgart · New York

Recent Advances in Catalytic Asymmetric Reactions of o-Quinone Methides

Zhaobin Wang
Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, P. R. of China   Email: sunjw@ust.hk
,
Jianwei Sun*
Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, P. R. of China   Email: sunjw@ust.hk
› Author Affiliations
Further Information

Publication History

Received: 30 August 2015

Accepted after revision: 14 September 2015

Publication Date:
21 October 2015 (online)


Abstract

This review summarizes recent advances in catalytic asymmetric reactions of o-quinone methides, an important family of species for organic synthesis. In the past decade, various catalytic systems have been developed for these reactions. This review is organized by the type of catalyst employed.

1 Introduction

2 Transition-Metal Catalysis

3 Phase-Transfer Catalysis

4 N-Heterocyclic Carbene Catalysis

5 Chiral Brønsted Acid Catalysis

6 Chiral Diol Catalysis

7 Bifunctional Chiral Brønsted Base Catalysis

8 Conclusion and Outlook