Synthesis of Isoselenocyanates

Abstract

Isoselenocyanates were synthesized by two methods under phase-transfer conditions (50% aq NaOH, CH₂Cl₂, Aliquat 336); the first started from isocyanides and selenium and gave isoselenocyanates in 61–89% yields, while the second started from amines and used chloroform and selenium, by applying sequentially the Hofmann isonitrile synthesis and the addition of selenium, in 4–70% yields.

Key words

isoselenocyanates - isocyanides - selenium - phase-transfer catalysis

• References

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