N-Bromosuccinimide-Mediated Synthesis of Substituted Quinoxalines

Abstract

An efficient and simple N-bromosuccinimide-mediated two-step synthesis of substituted quinoxalines from 1,2-diarylacetylenes and 1,2-diaminobenzenes in boiling AcOH, during a one-pot procedure has been developed. All the structures of the substituted quinoxalines were confirmed, some by single-crystal X-ray crystallography. Possible reaction pathways were discussed, and some data were matched with the previous work.

Key words

one-pot synthesis - N-bromosuccinimide - acetic acid - phenylacetylene - quinoxalines

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