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Synthesis 2016; 48(15): 2343-2360
DOI: 10.1055/s-0035-1561644
DOI: 10.1055/s-0035-1561644
short review
Recent Progresses towards the Strengthening of Cyclopropene Chemistry
Further Information
Publication History
Received: 07 April 2016
Accepted: 18 April 2016
Publication Date:
03 June 2016 (online)
Abstract
This short review focuses on the most relevant achievements in the field of cyclopropene chemistry including their syntheses, reactivities, and applications. As the chemistry of cyclopropenes has rapidly evolved in the last few years, valuable implementations on synthetic approaches are nowadays available. Moreover, exciting and useful applications by means of cyclopropenes in organic synthesis and other research areas have also been disclosed. Herein, an overview covering advances accomplished from 2011 until the beginning of 2016 is presented.
1 Introduction
2 Progress on Cyclopropene Syntheses
3 Reactivity of Cyclopropenes
3.1 Carbometalations and Related Reactions
3.2 Cycloisomerizations to Furan Derivatives and Related Reactions
3.3 Cyclopropene Isomerization to Vinyl Carbene Intermediates
3.4 Miscellanea of Reactions
4 Applications of Cyclopropenes
5 Conclusion
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For the pioneering discovery, see:
Selected examples:
For additional recent examples on carbometalations or addition of organometallics to cyclopropenes, see:
Some examples on this reactivity are disclosed in ref 10b. For an example of ruthenium-catalyzed cycloisomerization to furans, see:
Gold catalysts also allow access to furans; for a recent theoretical study, see:
For a phosphine-catalyzed cycloisomerization, see:
For recent reviews, see:
For theoretical studies on gold-catalyzed cyclopropene rearrangements, see ref 58b and:
See also:
See also:
For computational studies, see:
For other recent examples of cycloaddition reactions involving cyclopropenes, see:
See also:
For computational studies concerning this transformation, see:
For recent computational studies on the cycloaddition of tetrazines with cyclopropenes, see: