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Synthesis 2016; 48(20): 3589-3596
DOI: 10.1055/s-0035-1561656
DOI: 10.1055/s-0035-1561656
paper
Practical Method for the Preparation of 2,2-Dimethyl-5-{aryl[(hetero)aryl]methyl}-1,3-dioxane-4,6-diones: Synthesis and Mechanistic Study
Weitere Informationen
Publikationsverlauf
Received: 17. Februar 2016
Accepted after revision: 02. Mai 2016
Publikationsdatum:
10. Juni 2016 (online)
Abstract
An efficient practical synthetic procedure has been developed for the synthesis of 2,2-dimethyl-5-{aryl[(hetero)aryl]methyl}-1,3-dioxane-4,6-diones through Friedel–Crafts alkylation. The scope and limitation of the reaction of 2,2-dimethyl-5-arylidene-1,3-dioxane-4,6-diones with π-excess aromatic systems have been delineated.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1561656.
- Supporting Information
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