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Synlett 2016; 27(16): 2327-2332
DOI: 10.1055/s-0035-1562470
DOI: 10.1055/s-0035-1562470
letter
Facile Synthesis of Naphthothiophenone Derivatives and Anthradithiophenedione via Friedel–Crafts Acylation and Their Fundamental Properties
Further Information
Publication History
Received: 08 May 2016
Accepted after revision: 14 June 2016
Publication Date:
19 July 2016 (online)


Abstract
Facile synthetic methods for constructing naphthothiophenone and its π-extended derivatives were developed. Naphthothiophenone and anthradithiophenedione were synthesized by the S-acylation of thiol to form chlorothioformate and subsequent Friedel–Crafts acylation. A bromination reaction of naphthothiophenone and its application to Suzuki–Miyaura cross-coupling was also carried out. The fundamental physical properties of these compounds were also investigated.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1562470. Experimental procedures for all new compounds are included, as well as a cif file for compounds 3 (CCDC 1477938) and 11 (CCDC 1477982).
- Supporting Information