Journal of Pediatric Neuroradiology 2016; 05(01): 026-031
DOI: 10.1055/s-0036-1584285
Review Article
Georg Thieme Verlag KG Stuttgart • New York

Acute and Long-Term Outcomes Following Pediatric Traumatic Brain Injury

Robyn A. Howarth
1   Department of Neuropsychology, Children's Healthcare of Atlanta, Emory School of Medicine, Atlanta, Georgia, United States
,
Laura S. Blackwell
1   Department of Neuropsychology, Children's Healthcare of Atlanta, Emory School of Medicine, Atlanta, Georgia, United States
,
Kim E. Ono
1   Department of Neuropsychology, Children's Healthcare of Atlanta, Emory School of Medicine, Atlanta, Georgia, United States
› Author Affiliations
Further Information

Publication History

26 January 2016

26 January 2016

Publication Date:
30 May 2016 (online)

Abstract

Pediatric traumatic brain injury (TBI) is one of the leading causes of death and serious disability among children and adolescents. In this review, the neuropathology and pathophysiology of pediatric TBI will be briefly discussed, including the importance of advanced neuroimaging techniques to assist with acute management and diagnostic accuracy. Then, predictors of outcome and sequelae of injury will be highlighted, across TBI severities, including impact on health-related quality of life. Finally, a case study will be presented to highlight the unique trajectory and outcome in a teenager with a severe TBI.

 
  • References

  • 1 Centers for Disease Control and Prevention. Report to Congress on Traumatic Brain Injury in the United States: Epidemiology and Rehabilitation. Atlanta, GA: National Center for Injury Prevention and Control; Division of Unintentional Injury Prevention; 2010
  • 2 Bazarian JJ, McClung J, Shah MN, Cheng YT, Flesher W, Kraus J. Mild traumatic brain injury in the United States, 1998–2000. Brain Inj 2005; 19 (2) 85-91
  • 3 Lloyd J, Wilson ML, Tenovuo O, Saarijärvi S. Outcomes from mild and moderate traumatic brain injuries among children and adolescents: a systematic review of studies from 2008-2013. Brain Inj 2015; 29 (5) 539-549
  • 4 Giza CC, Mink RB, Madikians A. Pediatric traumatic brain injury: not just little adults. Curr Opin Crit Care 2007; 13 (2) 143-152
  • 5 Laskowitz D, Grant G. Translational Research in Traumatic Brain Injury. Boca Raton, FL: CRC Press; 2016
  • 6 Yeates KO. Traumatic brain injury. In: Yeates KO, Ris M, Taylor H, Pennington B, eds. Neuropsychology Research, Theory, and Practice. New York, NY: Guilford Press; 2010: 112-146
  • 7 Orrison WW, Gentry LR, Stimac GK, Tarrel RM, Espinosa MC, Cobb LC. Blinded comparison of cranial CT and MR in closed head injury evaluation. AJNR Am J Neuroradiol 1994; 15 (2) 351-356
  • 8 Bigler ED. Anterior and middle cranial fossa in traumatic brain injury: relevant neuroanatomy and neuropathology in the study of neuropsychological outcome. Neuropsychology 2007; 21 (5) 515-531
  • 9 Blackman JA, Rice SA, Matsumoto JA , et al. Brain imaging as a predictor of early functional outcome following traumatic brain injury in children, adolescents, and young adults. J Head Trauma Rehabil 2003; 18 (6) 493-503
  • 10 Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet 1974; 2 (7872) 81-84
  • 11 Suskauer SJ, Huisman TAGM. Neuroimaging in pediatric traumatic brain injury: current and future predictors of functional outcome. Dev Disabil Res Rev 2009; 15 (2) 117-123
  • 12 Ashwal S, Holshouser BA, Tong KA. Use of advanced neuroimaging techniques in the evaluation of pediatric traumatic brain injury. Dev Neurosci 2006; 28 (4–5) 309-326
  • 13 Martin C, Falcone Jr RA. Pediatric traumatic brain injury: an update of research to understand and improve outcomes. Curr Opin Pediatr 2008; 20 (3) 294-299
  • 14 Catroppa C, Anderson VA, Morse SA, Haritou F, Rosenfeld JV. Outcome and predictors of functional recovery 5 years following pediatric traumatic brain injury (TBI). J Pediatr Psychol 2008; 33 (7) 707-718
  • 15 Stevens CP, Raz S, Sander CJ. Peripartum hypoxic risk and cognitive outcome: a study of term and preterm birth children at early school age. Neuropsychology 1999; 13 (4) 598-608
  • 16 Anderson V, Catroppa C, Morse S, Haritou F, Rosenfeld JV. Intellectual outcome from preschool traumatic brain injury: a 5-year prospective, longitudinal study. Pediatrics 2009; 124 (6) e1064-e1071
  • 17 Taylor HG, Yeates K, Wade S, Drotar D, Stancin T, Montpetite M. Long-term educational interventions after traumatic brain injury in children. Rehabil Psychol 2003; 48 (4) 227-236
  • 18 Glang A, Todis B, Thomas CW, Hood D, Bedell G, Cockrell J. Return to school following childhood TBI: who gets services?. NeuroRehabilitation 2008; 23 (6) 477-486
  • 19 Brown G, Chadwick O, Shaffer D, Rutter M, Traub M. A prospective study of children with head injuries: III. Psychiatric sequelae. Psychol Med 1981; 11 (1) 63-78
  • 20 Wechsler B, Kim H, Gallagher PR, DiScala C, Stineman MG. Functional status after childhood traumatic brain injury. J Trauma 2005; 58 (5) 940-949 , discussion 950
  • 21 Schwartz L, Taylor HG, Drotar D, Yeates KO, Wade SL, Stancin T. Long-term behavior problems following pediatric traumatic brain injury: prevalence, predictors, and correlates. J Pediatr Psychol 2003; 28 (4) 251-263
  • 22 Yeates KO, Taylor HG, Drotar D , et al. Preinjury family environment as a determinant of recovery from traumatic brain injuries in school-age children. J Int Neuropsychol Soc 1997; 3 (6) 617-630
  • 23 Taylor HG, Yeates KO, Wade SL, Drotar D, Stancin T, Minich N. A prospective study of short- and long-term outcomes after traumatic brain injury in children: behavior and achievement. Neuropsychology 2002; 16 (1) 15-27
  • 24 Yeates KO, Swift E, Taylor HG , et al. Short- and long-term social outcomes following pediatric traumatic brain injury. J Int Neuropsychol Soc 2004; 10 (3) 412-426
  • 25 Anderson VA, Catroppa C, Haritou F, Morse S, Rosenfeld JV. Identifying factors contributing to child and family outcome 30 months after traumatic brain injury in children. J Neurol Neurosurg Psychiatry 2005; 76 (3) 401-408
  • 26 Anderson V, Moore C. Age at injury as a predictor of outcome following pediatric head injury: a longitudinal perspective. Child Neuropsychol 1995; 1: 187-202
  • 27 Taylor HG, Alden J. Age-related differences in outcomes following childhood brain insults: an introduction and overview. J Int Neuropsychol Soc 1997; 3 (6) 555-567
  • 28 Anderson V, Jacobs R, Spencer-Smith M , et al. Does early age at brain insult predict worse outcome? Neuropsychological implications. J Pediatr Psychol 2010; 35 (7) 716-727
  • 29 Donders J. Traumatic brain injury. In: Hunter SJ, Donders J, eds. Pediatric Neuropsychological Intervention. New York, NY: Cambridge University Press; 2007: 91-111
  • 30 Ylvisaker M, Feeney T. Pediatric brain injury: social, behavioral, and communication disability. Phys Med Rehabil Clin N Am 2007; 18 (1) 133-144 , vii
  • 31 McKinlay A, Grace R, Horwood J, Fergusson D, MacFarlane M. Adolescent psychiatric symptoms following preschool childhood mild traumatic brain injury: evidence from a birth cohort. J Head Trauma Rehabil 2009; 24 (3) 221-227
  • 32 Crowe LM, Catroppa C, Babl FE, Rosenfeld JV, Anderson V. Timing of traumatic brain injury in childhood and intellectual outcome. J Pediatr Psychol 2012; 37 (7) 745-754
  • 33 Satz P, Zaucha K, McCleary C, Light R, Asarnow R, Becker D. Mild head injury in children and adolescents: a review of studies (1970-1995). Psychol Bull 1997; 122 (2) 107-131
  • 34 Babikian T, Asarnow R. Neurocognitive outcomes and recovery after pediatric TBI: meta-analytic review of the literature. Neuropsychology 2009; 23 (3) 283-296
  • 35 Hanten G, Li X, Newsome M , et al. Oral reading and expressive language after childhood traumatic brain injury: trajectory and correlates of changes over time: prospective study. Top Lang Disord 2009; 29: 238-244
  • 36 Hanten G, Li X, Newsome M , et al. Oral reading and expressive language after childhood traumatic brain injury: trajectory and correlates of changes over time: retrospective study. Top Lang Disord 2009; 29: 244-248
  • 37 Kirkwood MW, Yeates KO, Taylor HG, Randolph C, McCrea M, Anderson VA. Management of pediatric mild traumatic brain injury: a neuropsychological review from injury through recovery. Clin Neuropsychol 2008; 22 (5) 769-800
  • 38 Jaffe KM, Fay GC, Polissar NL , et al. Severity of pediatric traumatic brain injury and early neurobehavioral outcome: a cohort study. Arch Phys Med Rehabil 1992; 73 (6) 540-547
  • 39 Anderson V, Le Brocque R, Iselin G , et al. Adaptive ability, behavior and quality of life pre and posttraumatic brain injury in childhood. Disabil Rehabil 2012; 34 (19) 1639-1647
  • 40 Fay TB, Yeates KO, Wade SL, Drotar D, Stancin T, Taylor HG. Predicting longitudinal patterns of functional deficits in children with traumatic brain injury. Neuropsychology 2009; 23 (3) 271-282
  • 41 Kinsella GJ, Prior M, Sawyer M , et al. Predictors and indicators of academic outcome in children 2 years following traumatic brain injury. J Int Neuropsychol Soc 1997; 3 (6) 608-616
  • 42 Fletcher JM, Ewing-Cobbs L, Miner ME, Levin HS, Eisenberg HM. Behavioral changes after closed head injury in children. J Consult Clin Psychol 1990; 58 (1) 93-98
  • 43 Dennis M, Guger S, Roncadin C, Barnes M, Schachar R. Attentional-inhibitory control and social-behavioral regulation after childhood closed head injury: do biological, developmental, and recovery variables predict outcome?. J Int Neuropsychol Soc 2001; 7 (6) 683-692
  • 44 Dennis M, Barnes MA, Wilkinson M, Humphreys RP. How children with head injury represent real and deceptive emotion in short narratives. Brain Lang 1998; 61 (3) 450-483
  • 45 Dennis M, Purvis K, Barnes MA, Wilkinson M, Winner E. Understanding of literal truth, ironic criticism, and deceptive praise following childhood head injury. Brain Lang 2001; 78 (1) 1-16
  • 46 Hanten G, Wilde EA, Menefee DS , et al. Correlates of social problem solving during the first year after traumatic brain injury in children. Neuropsychology 2008; 22 (3) 357-370
  • 47 Janusz JA, Kirkwood MW, Yeates KO, Taylor HG. Social problem-solving skills in children with traumatic brain injury: long-term outcomes and prediction of social competence. Child Neuropsychol 2002; 8 (3) 179-194
  • 48 Osberg JS, Brooke MM, Baryza MJ, Rowe K, Lash M, Kahn P. Impact of childhood brain injury on work and family finances. Brain Inj 1997; 11 (1) 11-24
  • 49 Hawley CA, Ward AB, Magnay AR, Long J. Parental stress and burden following traumatic brain injury amongst children and adolescents. Brain Inj 2003; 17 (1) 1-23
  • 50 Aitken ME, McCarthy ML, Slomine BS , et al; CHAT Study Group. Family burden after traumatic brain injury in children. Pediatrics 2009; 123 (1) 199-206
  • 51 Varni JW, Seid M, Kurtin PS. PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations. Med Care 2001; 39 (8) 800-812
  • 52 WHOQOL Group. The World Health Organization Quality of Life Assessment (WHOQOL): development and general psychometric properties. Soc Sci Med 1998; 46 (12) 1569-1585
  • 53 Wells R, Minnes P, Phillips M. Predicting social and functional outcomes for individuals sustaining paediatric traumatic brain injury. Dev Neurorehabil 2009; 12 (1) 12-23
  • 54 Brown EA, Kenardy J, Chandler B, Anderson V, McKinlay L, Le Brocque R. Parent-reported health related quality of life in children with traumatic brain injury: a prospective study. J Pediatr Psychol 2016; 41 (2) 244-255
  • 55 Rivara FP, Koepsell TD, Wang J , et al. Disability 3, 12, and 24 months after traumatic brain injury among children and adolescents. Pediatrics 2011; 128 (5) e1129-e1138
  • 56 Limond J, Dorris L, McMillan TM. Quality of life in children with acquired brain injury: parent perspectives 1-5 years after injury. Brain Inj 2009; 23 (7) 617-622
  • 57 Erickson SJ, Montague EQ, Gerstle MA. Health-related quality of life in children with moderate-to-severe traumatic brain injury. Dev Neurorehabil 2010; 13 (3) 175-181
  • 58 Yeates KO, Taylor HG, Wade SL, Drotar D, Stancin T, Minich N. A prospective study of short- and long-term neuropsychological outcomes after traumatic brain injury in children. Neuropsychology 2002; 16: 514-523
  • 59 Holland S, Silberstein SD, Freitag F, Dodick DW, Argoff C, Ashman E ; Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology 2012; 78 (17) 1346-1353
  • 60 Management of Concussion/mTBI Working Group. VA/DoD clinical practice guideline for management of concussion/mild traumatic brain injury. J Rehabil Res Dev 2009; 46 (6) CP1-CP68