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DOI: 10.1055/s-0036-1584552
Extra-Axial Cerebello-Pontine Angle Medulloblastoma
Meduloblastoma extra-axial no ângulo ponto-cerebelarPublikationsverlauf
16. August 2015
08. April 2016
Publikationsdatum:
14. Juni 2016 (online)
Abstract
Medulloblastoma is the most common central nervous system tumor in children. Extra-axial medulloblastomas, especially tumors with no connection to the brain stem or cerebellum are extremely rare. We report a case of a 3-year-old patient, who presented with a history of subacute headache and vomiting. After performing a head computed tomography scan, a mass was detected in the left cerebello-pontine angle, along with concomitant hydrocephalus. The treatment was total resection of the tumor. Despite the fact that extra-axial medulloblastomas are extremely rare, this differential diagnosis should be included in the management of pediatric patients who present with posterior fossa tumors.
Resumo
Meduloblastoma é o tumor do sistema nervoso central mais comum em crianças. Meduloblastomas extra-axiais, especialmente tumores sem conexão com o tronco encefálico ou cerebelo, são extremamente raros. Relatamos o caso de uma paciente de 3 anos de idade, que apresentou um histórico de cefaleia subaguda e vômitos. Por meio de um exame de tomografia computadorizada, foi identificada uma massa no ângulo ponto-cerebelar esquerdo, acompanhada de hidrocefalia. O tratamento foi resseção total do tumor. Apesar de meduloblastomas extra-axiais serem extremamente raros, este diagnóstico diferencial deve ser incluído no manejo de pacientes pediátricos que apresentem tumores da fossa posterior.
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References
- 1 Youmans JR. Neurological Surgery. 6th Edition. W.B. Saunders Company; 2011
- 2 Yamada S, Aiba T, Hara M. Cerebellopontine angle medulloblastoma: case report and literature review. Br J Neurosurg 1993; 7 (1) 91-94
- 3 Kumar R, Bhowmick U, Kalra SK, Mahapatra AK. Pediatric cerebellopontine angle medulloblastomas. J Pediatr Neurosci 2008; 3 (2) 127-130
- 4 Bahrami E, Bakhti S, Fereshtehnejad SM, Parvaresh M, Khani MR. Extra-axial medulloblastoma in cerebello-pontine angle: A report of a rare case with literature review. Med J Islam Repub Iran 2014; 28: 57
- 5 Fallah A, Banglawala SM, Provias J, Jha NK. Extra-axial medulloblastoma in the cerebellopontine angle. Can J Surg 2009; 52 (4) E101-E102
- 6 Gil-Salú JL, Rodríguez-Peña F, López-Escobar M, Palomo MJ. [Medulloblastoma presenting as an extra-axial tumor in the cerebellopontine angle]. Neurocirugia (Astur) 2004; 15 (3) 285-289
- 7 McLendon RE, Rosenblum MK, Bigner DD , Eds. Russell & Rubinstein's Pathology of Tumors of the Nervous System. 7th Ed. New York: Oxford University Press Inc.; 2006: 247-260
- 8 Petritsch C, Vandenberg SR. Stem cells and progenitor cell lineages as targets for neoplastic transformation in the central nervous system. In: Kaye AH, Laws Jr ER. Brain Tumors. 3rd Ed. New York: Elsevier; 2012. . Chap. 2. p. 12-15
- 9 Ciurea AV, Palade C. Medulloblastoma: An Overview. Romanian Neurosurgery. Bucareste 2010; 17 (3) 291-303
- 10 Frosch MP, Anthony DC, Girolam U. O Sistema Nervoso Central: Tumores. In: Kumar V, Abbas Ak, Fausto N. Robbins & Cotran Patologia: Bases Patológicas Das Doenças. 8th Ed. São Paulo: Elsevier; 2010. (28): 1338-1351
- 11 MacDonald TJ, Rood BR, Santi MR , et al. Advances in the diagnosis, molecular genetics, and treatment of pediatric embryonal CNS tumors. Oncologist 2003; 8 (2) 174-186
- 12 Meshkini A, Vahedi A, Meshkini M, Alikhah H, Naghavi-Behzad M. Atypical medulloblastoma: A case series. Asian J Neurosurg 2014; 9 (1) 45-47
- 13 Koeller KK, Rushing EJ. From the archives of the AFIP: medulloblastoma: a comprehensive review with radiologic-pathologic correlation. Radiographics 2003; 23 (6) 1613-1637
- 14 Fruehwald-Pallamar J, Puchner SB, Rossi A , et al. Magnetic resonance imaging spectrum of medulloblastoma. Neuroradiology 2011; 53 (6) 387-396
- 15 Hubbard JL, Scheithauer BW, Kispert DB, Carpenter SM, Wick MR, Laws Jr ER. Adult cerebellar medulloblastomas: the pathological, radiographic, and clinical disease spectrum. J Neurosurg 1989; 70 (4) 536-544
- 16 Holst B, Grunwald IQ, Brill G, Reith W. [Differential diagnosis of space demands in the cerebellopontine angle]. Radiologe 2004; 44 (11) 1113-1136 , quiz 1137