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Journal of Pediatric Biochemistry 2010; 01(04): 325-329
DOI: 10.1055/s-0036-1586383
Review Article
Georg Thieme Verlag KG Stuttgart – New York

Nitric oxide: A promising biomarker for respiratory disorders

Nidhi Anil
a   Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Meenu Singh
a   Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
› Author Affiliations
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Publication History

02 February 2011

04 March 2011

Publication Date:
01 August 2016 (online)

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Abstract

Nitric oxide (NO) is a ubiquitous messenger molecule with multiple roles in cellular physiology and signaling. Recent studies have indicated the role of NO as an inflammatory mediator and as a potential non invasive biomarker. The current review focuses on the role of nitric oxide and its derivatives including nitrites as potential non invasive biomarkers for assessing airway inflammation in respiratory disorders including asthma, bronchiectasis, cystic fibrosis and chronic obstructive pulmonary disease.

Keywords

Nitric oxide - nitrite - biomarkers - airway inflammation