RSS-Feed abonnieren
DOI: 10.1055/s-0036-1586406
Serum lipids and lipoprotein(a) levels in children with idiopathic nephrotic syndrome
Verantwortlicher Herausgeber dieser Rubrik:
Publikationsverlauf
02. Januar 2012
30. Januar 2012
Publikationsdatum:
01. August 2016 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00029022/201203/lookinside/thumbnails/10-1055-s-0036-1586406_00051-1.jpg)
Abstract
The present study was carried out prospectively to evaluate serum lipids and lipoprotein(a) levels in children with nephrotic syndrome during the active phase of disease and during a remission. Serum lipids and lipoprotein(a) levels were measured in 40 children, aged 2–10 years, during the active phase of nephrotic syndrome; 25 with a first attack, 9 infrequent relapsers and 6 frequent relapsers, and during remission and in 20 healthy age-matched controls. The mean serum lipids and lipoprotein(a) levels were significantly raised during the active phase of nephrotic syndrome (p < 0.001). The values were relatively higher in relapsers. The lipids and lipoprotein(a) levels decreased during a remission but were significantly higher (p < 0.05) than controls. Serum lipids had a negative correlation with serum albumin and lipoprotein(a) had a positive correlation with proteinuria (r = 0.5246, p < 0.01) but no correlation with serum albumin. The elevated lipids and lipoprotein(a) in both the active phase of nephrotic syndrome and during remission suggest a possible predisposition to atherosclerosis in future.