Synthesis 2017; 49(05): 1122-1130
DOI: 10.1055/s-0036-1588327
paper
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Alkoxymethyl Groups Containing Isoxazoles and Chromones

Mantas Jonušis
Department of Organic Chemistry, Faculty of Chemistry, Vilnius University, Naugarduko 24, Vilnius 03225, Lithuania   eMail: inga.cikotiene@chf.vu.lt
,
Lukas Šteinys
Department of Organic Chemistry, Faculty of Chemistry, Vilnius University, Naugarduko 24, Vilnius 03225, Lithuania   eMail: inga.cikotiene@chf.vu.lt
,
Rita Bukšnaitienė
Department of Organic Chemistry, Faculty of Chemistry, Vilnius University, Naugarduko 24, Vilnius 03225, Lithuania   eMail: inga.cikotiene@chf.vu.lt
,
Inga Čikotienė*
Department of Organic Chemistry, Faculty of Chemistry, Vilnius University, Naugarduko 24, Vilnius 03225, Lithuania   eMail: inga.cikotiene@chf.vu.lt
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received: 01. August 2016

Accepted after revision: 12. September 2016

Publikationsdatum:
14. Oktober 2016 (online)


Abstract

An oxocarbenium ion mediated cyclization of (Z)-1,3-diarylprop-2-yn-1-one O-methyloximes and 3-arylprop-2-yn-1-(2-methoxyphenyl)-1-ones resulted in regioselective formation of functionalized isoxazoles and chromones, respectively. Alkoxy(aryl)methyl group containing compounds were obtained in good and high yields.

Supporting Information

 
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