Enamine-Mediated 1,3-Dipolar Cycloaddition Reaction of Curcumin Derivatives with Azides: Direct Access to 1,4,5-Trisubstituted 1,2,3-Triazoles

Abstract

An enamine-mediated [3+2] organocatalytic 1,3-dipolar cy­cloaddition reaction of curcumin derivatives with azides has been developed. This strategy could generate 1,4,5-trisubstituted 1,2,3-triazoles in high yields and regioselectivities under mild conditions.

Key words

enamines - azides - 1,3-dipolar cycloadditions - curcumin derivatives - 1,2,3-triazoles

• References

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