Recent Advances in Amide Reductions

Abstract

This short review highlights recent advances in amide reductions. The last two years have witnessed important developments with milestones reached in catalytic hydrogenations and hydrosilylations. While metal-catalyzed processes still focus tremendous efforts from the scientific community, methodologies based on the metal-free hydrosilylation of amides have definitively joined the competition.

1 Introduction

2 Recent Use of Stoichiometric Reducing Reagents

3 Hydrogenations

4 Hydrosilylations

5 Conclusion and Outlook

Key words

amides - hydrides - reduction - hydrogenation - hydrosilylation

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