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DOI: 10.1055/s-0036-1591719
Borane-Catalysed Hydroboration of Alkynes and Alkenes
Publikationsverlauf
Received: 04. September 2017
Accepted after revision: 10. Oktober 2017
Publikationsdatum:
20. November 2017 (online)
![](https://www.thieme-connect.de/media/synthesis/201804/lookinside/thumbnails/ss-2017-z0575-op_10-1055_s-0036-1591719-1.jpg)
Published as part of the Bürgenstock Special Section 2017 Future Stars in Organic Chemistry
Abstract
Simple, commercially available borane adducts, H3B·THF and H3B·SMe2, have been used to catalyse the hydroboration of alkynes and alkenes with pinacolborane to give the alkenyl and alkyl boronic esters, respectively. Alkynes and terminal alkenes underwent highly regioselective hydroboration to give the linear boronic ester products. Good functional group tolerance was observed for substrates bearing ester, amine, ether and halide substituents. This catalytic process shows comparable reactivity to transition-metal-catalysed hydroboration protocols.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1591719.
- Supporting Information
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