CC BY-ND-NC 4.0 · SynOpen 2018; 02(01): 0030-0035
DOI: 10.1055/s-0036-1591917
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Synthesis of 3-(4-(Benzo[d]thiazol-2-yl)phenyl)-5-aryl-1,3,5-oxadiazinane-4-thiones and 1-(4-(Benzo[d]thiazol-2-yl)phenyl)-5-methyl-3-aryl-1,3,5-triazinane-2-thiones

Pathki Uma
,
,
Yelike Hemanth Sriram
,
Akarapu Premalatha
,
Pondichery Kuppuswamy Saipraksh
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Publication History

Received: 19 November 2017

Accepted after revision: 15 January 2018

Publication Date:
31 January 2018 (online)


Abstract

In this investigation 4-(benzo[d]thiazol-2-yl)benzenamine was reacted with aryl isothiocyanates to give 1-(4-(benzo[d]thiazol-2-yl)phenyl)-3-aryl thioureas 2, which were cyclized with acid to afford 3-(4-(benzo[d]thiazol-2-yl)phenyl)-5-aryl-1,3,5-oxadiazinane-4-thiones 3. On the other hand, 1-(4-(benzo[d]thiazol-2-yl)phenyl)-5-methyl-3-aryl-1,3,5-triazinane-2-thiones 4 were obtained when compounds 2 were treated with amines.

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