Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000083.xml
Synlett 2018; 29(09): 1152-1156
DOI: 10.1055/s-0036-1591981
DOI: 10.1055/s-0036-1591981
letter
Controlled Aerobic Oxidation of Primary Benzylic Alcohols to Aldehydes Catalyzed by Polymer-Supported Triazine-Based Dendrimer–Copper Composites
This work was supported by the JST-ACCEL program (JPMJAC401). We are also grateful for funding from the JSPS KAKENHI [Grant-in-Aid for Challenging Exploratory Research (No. 26620090); for Young Scientists (No. 26810099), for Scientific Research (C) (No. 16K05876), and for JSPS Fellows (No. 15F15039)]. S.P. acknowledges financial support from the Japan Society for Promotion of Sciences (JSPS; Postdoctoral Fellowship for Overseas Researchers).Further Information
Publication History
Received: 27 February 2018
Accepted after revision: 14 March 2018
Publication Date:
09 April 2018 (online)


Abstract
A controlled aerobic oxidation of primary benzylic alcohols to the corresponding benzaldehydes by using polystyrene–poly(ethylene glycol) (PS–PEG) resin-supported triazine-based polyethyleneamine dendrimer–copper complexes [PS–PEG-TD2–Cu(II)] was developed. In particular, PS–PEG-TD2–Cu(OAc)2 efficiently catalyzed the aerobic oxidation of benzylic alcohols in the presence of a catalytic amount of TEMPO under atmospheric conditions to give the corresponding aldehydes in up to quantitative yield. The catalyst was readily recovered by simple filtration and reused four times without significant loss of its catalytic activity.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1591981 and from the author.
- Supporting Information