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Journal of Pediatric Biochemistry 2016; 06(03): 152-155
DOI: 10.1055/s-0036-1597607
DOI: 10.1055/s-0036-1597607
Original Article
Association of Thiol Disulfide Homeostasis with Childhood Asthma
Weitere Informationen
Publikationsverlauf
29. März 2016
11. November 2016
Publikationsdatum:
20. Dezember 2016 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00029022/201603/lookinside/thumbnails/10-1055-s-0036-1597607_1600004-1.jpg)
Abstract
The aim of this study is to evaluate the oxidative stress level in asthmatic children in terms of the disulfide/thiol ratio, to research the role the disulfide/thiol ratio plays in the pathogenesis of the malady, and to determine the usefulness of the disulfide/thiol ratio as an indicator of the oxidation stress situations in patients with asthma. We report that the disulfide/thiol ratio and disulfide levels were significantly higher in the asthmatic group than in the control group. All in all, high levels of disulfide/thiol ratios in asthmatic children are thought to play roles in the pathogenesis of the disease.
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