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Digestive Disease Interventions 2017; 01(01): 047-052
DOI: 10.1055/s-0037-1600117
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Locoregional Therapy for Cholangiocarcinoma

Nathan E. Frenk
1   Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
,
Ronald S. Arellano
1   Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
› Author Affiliations
Further Information

Publication History

06 December 2016

03 February 2017

Publication Date:
20 March 2017 (online)

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Abstract

Cholangiocarcinoma represents the second most common primary hepatic malignancy and carries an overall poor prognosis. While surgical resection offers the only chances for cure, few patients are surgical candidates at the time of diagnosis. Chemotherapeutic treatment with gemcitabine and cisplatin is the standard chemotherapeutic regimen, but this offers only marginal overall survival benefits. With advances in minimally invasive techniques in the past decade, locoregional therapies with thermal ablation and transarterial techniques are increasingly being investigated as treatment options. This review explores emerging technologies and their potential role in treating cholangiocarcinoma.

Keywords

locoregional therapy - cholangiocarcinoma - intrahepatic cholangiocarcinoma - thermal ablation - transarterial chemoembolization - radioembolization
 

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