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Neuropediatrics 2017; 48(06): 463-466
DOI: 10.1055/s-0037-1603642
Short Communication
Georg Thieme Verlag KG Stuttgart · New York

Morning Glory Disc Anomaly Associated with Ipsilateral Optic Nerve and Chiasm Thickening: Three Cases and Review of the Literature

Chiara Doneda
1   Department of Pediatric Radiology and Neuroradiology, Children's Hospital V Buzzi, ASST. Fatebenefratelli Sacco, Milan, Italy
,
Lorenzo Pinelli
2   Department of Diagnostic Imaging, Neuroradiology Unit, Section of Pediatric Neuroradiology, ASST Spedali Civili, Brescia, Italy
,
Matteo Scaramuzzi
3   San Giuseppe Hospital, University Eye Clinic, Milan, Italy
4   Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
,
Jessica Galli
5   Unit of Child Neurology and Psychiatry, ASST Spedali Civili, Brescia, Italy
6   Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy
,
Elisa Fazzi
5   Unit of Child Neurology and Psychiatry, ASST Spedali Civili, Brescia, Italy
6   Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy
,
Cecilia Parazzini
1   Department of Pediatric Radiology and Neuroradiology, Children's Hospital V Buzzi, ASST. Fatebenefratelli Sacco, Milan, Italy
,
Andrea Righini
1   Department of Pediatric Radiology and Neuroradiology, Children's Hospital V Buzzi, ASST. Fatebenefratelli Sacco, Milan, Italy
,
Paolo Nucci
3   San Giuseppe Hospital, University Eye Clinic, Milan, Italy
4   Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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Publikationsverlauf

29. November 2016

25. April 2017

Publikationsdatum:
09. Juni 2017 (online)

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Abstract

Several extraorbital findings have been described in morning glory disc anomaly (MGDA), including optic pathway abnormalities. We want to emphasize the importance of looking for ipsilateral optic nerve and chiasm thickening in MGDA-affected patients because we think that it may be a relevant common associated finding to date not stressed by anyone. We report three cases of clinically diagnosed unilateral MGDA in which magnetic resonance imaging revealed enlargement of the ipsilateral optic nerve and chiasm. A literature analysis was made and previously reported MGDA cases, and case series were checked, looking for described, or misunderstood similar magnetic resonance imaging findings. Three other cases with very similar prechiasmatic optic nerve and chiasm findings were identified from the literature. Two further cases are discussed as possibly characterized by similar misinterpreted magnetic resonance features. Our study broadens the constellation of intra- and extraorbital findings of MGDA. Though magnetic resonance imaging is not sufficient to determine the neuropathological substrate of this finding, clinicians and radiologists should be aware of the possible association of MGDA with ipsilateral thickening of the optic nerve and chiasm, to properly plan the clinical and imaging follow-up.

Keywords

morning glory disc anomaly - optic nerve - MRI

Note

No grant support has been given for this study.


 

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