Abstract
The use of blood transfusion in cardiac surgery varies widely. The beneficial effects
of blood products are offset by an increase in morbidity and mortality. Despite multiple
studies showing an association between blood product exposure and adverse short- and
long-term events, it is difficult to determine causality. Nevertheless, the implication
is sufficient to warrant the search for alternative strategies to reduce the use of
blood products while providing a standard of care that optimizes postoperative outcomes.
Aortic surgery, in particular, is associated with an increased risk of bleeding requiring
a blood transfusion. There is a paucity of evidence within aortic surgery regarding
the deleterious effects of blood products. Here, we review the current evidence regarding
patient outcomes after blood transfusion in cardiac surgery, with special emphasis
on aortic surgery.
Keywords
cardiac surgical procedures - thoracic surgery - thoracic aorta - blood transfusion
- morbidity - mortality - thoracic aortic aneurysm - dissection