Mass production method of Korea ginseng(Panax ginseng C.A. Meyer) leaf and inhibitory effect of extracts on fat accumulation

We have mostly used the root part of Korean ginseng as a fresh ginseng, red ginseng and white ginseng. Top part of ginseng is known that it has 3˜5 times more saponin than the ground part. Meanwhile, in terms of medicinal effect the value of the top part has been approved, but it hasn't been used due to the rearing relation of the ground part and the use of chemicals. In this study, we aimed to find out how to develope the mass production method of Korea ginseng's leaf that has a high practical value in facility and fat accumulation depressor effect to an animal. The mass production of the ginseng leaf was tried for the first time in Korea and we could mass-produce ginseng leaf in a vinyl greenhouse facility shaded 85% of the light with the density of seeding in 300˜400plant/1.62 m² by installing 100 cm width, 50 cm height, and 18 m length of a left and right direction movable cultivation bed. The yield of the top part of 3-year old ginseng was 3,471 kg/ha, which is the highest in 350plant/1.62 m² process. It significantly reduced the amount of weight, epididymis and abdominal fat tissue in injection of the extract from Green leaf (GL) and Aging leaf (AL) to a high fat diet (HFD) inducement rat. AL extract restrained fat formation of 3T3-L1 fat cell through the revelation control of the lipogenetic regulator like PPAR-γ and CCAAT/enhancer-binding protein (C/EBP)-α. In terms of the application of Korean ginseng leaf, the inhibition function of fat accumulation, which is not only fresh leaf but also aging leaf with chlorophyll-destroyed, will have considerable implications for ginseng cultivation and utilization.