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Clin Colon Rectal Surg 2018; 31(02): 121-126
DOI: 10.1055/s-0037-1609027
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Meconium Ileus

John H.T. Waldhausen
1   Department of Surgery, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington
,
Morgan Richards
1   Department of Surgery, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington
› Author Affiliations
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Publication History

Publication Date:
25 February 2018 (online)

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Abstract

Cystic fibrosis is one of the most common inheritable traits in Caucasians. Meconium ileus and its potential complications are the most likely reasons that these patients will need surgical care. Surgical intervention is usually needed in the neonatal period but may also be required later in life. This article discusses the various ways cystic fibrosis can affect the gastrointestinal tract. Both the operative and nonoperative management of complicated and uncomplicated meconium ileus are discussed in the neonatal period as well as long-term issues, such as distal intestinal obstructive syndrome, fibrosing colonopathy, and rectal prolapse, all of which may be seen in older children and adults.

Keywords

meconium ileus - cystic fibrosis - cystic fibrosis transmembrane conductance regulator - distal intestinal obstruction syndrome - epithelial sodium channels - fibrosing colonopathy - rectal prolapse - newborn intestinal obstruction
 

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