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CC BY ND NC 4.0 · SynOpen 2018; 02(02): 0145-0149
DOI: 10.1055/s-0037-1609517
DOI: 10.1055/s-0037-1609517
paper
Synthesis of Phthalimides: A New Entry via TBAI-Catalyzed Intramolecular Cyclization of 2-(Hydroxymethyl)benzamides
K. N. and N. R. thank CSIR New Delhi for Research Fellowships. This research work was financially supported by the CSIR, New Delhi (BSC 0116).Further Information
Publication History
Received: 21 March 2018
Accepted after revision: 19 April 2018
Publication Date:
16 May 2018 (online)
Communication No. IICT/Pubs./2018/080
Abstract
Herein we report an unprecedented metal-free TBAI/TBHP mediated C–N bond formation via intramolecular cyclization of 2-(hydroxymethyl)benzamides to furnish N-substituted phthalimides in excellent yields.
Keywords
phthalimide - intramolecular cyclization - transition-metal free - C–N bond formation - oxidationSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1609517.
- Supporting Information
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