Synthesis of the Proposed Structure of Cryptoconcatone H

Abstract

A synthesis of the proposed structure of cryptoconcatone H and one diastereoisomer has been achieved, featuring a tandem deprotection–oxa-Michael addition to establish the tetrahydropyran moiety. Comparison of the NMR spectroscopic data confirms that the original structural assignment was incorrect.

Key words

tetrahydropyran - Michael addition - metathesis - stereochemistry - tandem reaction

• References

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