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Synthesis 2018; 50(17): 3460-3466
DOI: 10.1055/s-0037-1610070
DOI: 10.1055/s-0037-1610070
paper
Radical Addition/Cyclization Cascade: An Efficient Approach to Nitro-Containing Quinoline-2,4(1H,3H)-diones
We acknowledge the financial support from the National Natural Science Foundation of China (No. 21662021), the Applied Basic Research Foundation of Yunnan Province (2016DC032), and the Analysis and Testing Foundation of Kunming University of Science and Technology (2016T20130138, 20150725).Weitere Informationen
Publikationsverlauf
Received: 28. März 2018
Accepted after revision: 28. April 2018
Publikationsdatum:
18. Juni 2018 (online)
![](https://www.thieme-connect.de/media/synthesis/201817/lookinside/thumbnails/ss-2018-f0213-op_10-1055_s-0037-1610070-1.jpg)
Abstract
A radical addition/cyclization cascade of o-cyanoarylacrylamides with magnesium nitrate hexahydrate is developed. This reaction exhibits good functional group tolerance and wide substrate scope, provides a highly efficient and practical access to nitro-containing quinoline-2,4(1H,3H)-diones.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1610069.
- Supporting Information
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