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DOI: 10.1055/s-0037-1610085
Recent Developments in Visible-Light-Catalyzed Multicomponent Trifluoromethylation of Unsaturated Carbon–Carbon Bonds
This work was supported by Korea Research Institute of Chemical Technology (Grant No. KK 1803-C00, KK 1803-B01 and BS.K18M101)Publication History
Received: 16 April 2018
Accepted after revision: 02 May 2018
Publication Date:
16 July 2018 (online)
Published as part of the Special Topic Photoredox Methods and their Strategic Applications in Synthesis
Abstract
Trifluoromethylation has emerged as an important tool for modulating the molecular chemical and physical properties in material, polymer, and medicinal chemistry. In particular, photocatalyzed trifluoromethylation in the presence of visible-light irradiation has potentially different activity under mild conditions compared with traditional methods. This review summarizes the recent advances in trifluoromethylation with multiple bond system such as alkynes and alkenes.
1 Introduction
2 Trifluoromethylating Reagents
3 Multicomponent Reactions of Alkynes
4 Multicomponent Reactions of Alkenes
5 Conclusion