CC BY 4.0 · SynOpen 2018; 02(02): 0213-0221
DOI: 10.1055/s-0037-1610167
paper
Copyright with the author

Room Temperature, Open-Flask C–P Bond-Formation on Water under Catalyst-Free Conditions

Rakhee Choudhary
MFOS Laboratory, Department of Chemistry (Centre of Advanced Study), University of Rajasthan, JLN Marg, Jaipur, Rajasthan-302004, India   Email: badsarass4@uniraj.ac.in   Email: sattubhu2005@gmail.com
,
Rekha Bai
MFOS Laboratory, Department of Chemistry (Centre of Advanced Study), University of Rajasthan, JLN Marg, Jaipur, Rajasthan-302004, India   Email: badsarass4@uniraj.ac.in   Email: sattubhu2005@gmail.com
,
Pratibha Singh
MFOS Laboratory, Department of Chemistry (Centre of Advanced Study), University of Rajasthan, JLN Marg, Jaipur, Rajasthan-302004, India   Email: badsarass4@uniraj.ac.in   Email: sattubhu2005@gmail.com
,
Mahesh C. Sharma
MFOS Laboratory, Department of Chemistry (Centre of Advanced Study), University of Rajasthan, JLN Marg, Jaipur, Rajasthan-302004, India   Email: badsarass4@uniraj.ac.in   Email: sattubhu2005@gmail.com
,
MFOS Laboratory, Department of Chemistry (Centre of Advanced Study), University of Rajasthan, JLN Marg, Jaipur, Rajasthan-302004, India   Email: badsarass4@uniraj.ac.in   Email: sattubhu2005@gmail.com
› Author Affiliations
The authors thank SERB-DST, New Delhi (YSS/2015/001870), DST- New Delhi for INSPIRE Faculty Award (IFA-2014/CH-167) and the Council of Scientific& Industrial Research-India (02(0341)/18/EMR-II).

Further Information

Publication History

Received: 31 March 2018

Accepted after revision: 08 May 2018

Publication Date:
13 June 2018 (online)


‡Authors contributed equally

Abstract

A catalyst-free C–P bond-formation in an open flask at room temperature between isatin derivatives and phosphorus surrogates on water is described. Isatin derivatives possessing different substitutes underwent C–P coupling reaction with a variety of phosphine oxides under the reaction conditions employed, providing the desired products in up to quantitative yields.

Supporting Information