Synthesis of 1-Carboxamide-1,4-dihydropyridazines via Recycli­zation of Hydroxypyrrolines with Semicarbazides

Abstract

Recyclization of available 5-hydroxypyrrolines with semicarbazide and its analogues has been studied. As a result, rare 1,4-dihydropyridazines with carboxamide function at the N-1 atom have been synthesized in up to 88% isolated yields.

Key words

dihydropyridazine - semicarbazide - hydroxypyrroline - carboxamide - DFT studies

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