Abstract
For some aromatics, a twofold C–H deprotolithiation can be achieved, allowing these compounds to be subsequently difunctionalized in one step. This short review brings together examples in which ferrocenes are converted in this way.
1 Introduction
2 Bare Ferrocene
3 Ferrocenes Substituted by Alkyl or Silyl Groups
4 Ferrocenes Substituted by Aminoalkyls
5 Ferrocenes Substituted by Halogens or Oxygen-Based Groups
6 Ferrocenes Substituted by Alkoxyalkyls or Acetals
7 Ferrocenes Substituted by Sulfoxides
8 Ferrocenes Substituted by Oxazolines
9 Ferrocenes Substituted by Carboxamides
10 Conclusion
Key words
ferrocene - deprotolithiation - dilithio compounds - electrophilic trapping - planar chirality - chiral directing group - chiral ligand - ferrocenophane
