Synlett 2019; 30(14): 1719-1724
DOI: 10.1055/s-0037-1610723
letter
© Georg Thieme Verlag Stuttgart · New York

NHC-Catalyzed Synthesis of Benzazole-Phosphine Ligands under an Air Atmosphere

Wei Ren
a   State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. of China
,
Qian-Ming Zuo
a   State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. of China
,
Shang-Dong Yang
a   State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. of China
b   State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, P. R. of China   Email: yangshd@lzu.edu.cn
› Author Affiliations
Funding was provided by the National Natural Science Foundation of China (NSFC; No. 21532001) and by the Open Fund of the Key Laboratory of Functional Molecular Engineering of Guangdong Province (2016kf04).
Further Information

Publication History

Received: 11 June 2019

Accepted after revision: 04 July 2019

Publication Date:
24 July 2019 (online)


Abstract

An efficient strategy for the synthesis of benzazole-phosphine ligand precursors via N-heterocyclic carbene catalyzed aerobic oxidative cyclization reaction has been performed. The reaction displays broad functional group tolerance and high atom economy, and the transformation has been further applied to benzazole-phosphine ligand synthesis.

Supporting Information