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DOI: 10.1055/s-0037-1610844
The Preparation of Tetramethyl 1,1′,3,3′-Ruthenocenetetracarboxylate and Tetramethyl 1,1′,3,3′-Osmocenetetracarboxylate, and a Simplified Synthesis for Tetramethyl 1,1′,3,3′-Ferrocenetetracarboxylate
Publikationsverlauf
Received: 06. September 2018
Accepted after revision: 18. Oktober 2018
Publikationsdatum:
12. Dezember 2018 (online)
Dedicated to Jean-Pierre Praly on his 70th birthday
Abstract
Substituted metallocenes with more than two substituents have to be synthesized using doubly substituted cyclopentadiene rings in a reaction with a metal compound or by the introduction of additional functional groups to an already di-substituted metallocene. The direct formation of tetra-substituted metallocenes often suffers due to insufficient reactivity of the reagents or the resulting product mixtures, which are hard to separate. In this work, a protocol, which was successful in a tetra-substitution of ferrocene by a tetra-metalation followed by a reaction with carbon dioxide, is used to perform the tetra-substitution of ruthenocene and osmocene. In addition, a simplified protocol for the tetra-functionalization of ferrocene using commercially available components on a medium scale is described.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1610844.
- Supporting Information
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