CC BY-ND-NC 4.0 · SynOpen 2019; 03(01): 36-45
DOI: 10.1055/s-0037-1611679
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Stereoselective Synthesis of 4-O-Tosyltetrahydropyrans via Prins Cyclization Reaction of Enol Ethers

Sujit Sarkar
,
Namita Devi
,
Bikoshita Porashar
,
Santu Ruidas
,
Anil K Saikia*
This work is supported by the Department of Science and Technology (DST), New Delhi (Grant No. EMR/2016/006411), and CoE, MHRD, Government of India.
Further Information

Publication History

Received: 20 January 2019

Accepted after revision: 05 February 2019

Publication Date:
28 February 2019 (online)


Abstract

Intramolecular cyclization of enol ethers mediated by para-toluenesulfonic acid leads to substituted tetrahydropyrans in good to moderate yields. The reaction is diastereoselective.

Supporting Information