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Synthesis 2019; 51(11): 2252-2260
DOI: 10.1055/s-0037-1611796
DOI: 10.1055/s-0037-1611796
short review
The Chemical Syntheses of Nannocystins
Start-up funds from SUNY-Albany are greatly acknowledged.Further Information
Publication History
Received: 12 March 2019
Accepted after revision: 21 March 2019
Publication Date:
17 April 2019 (online)
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Abstract
The broad and potent anticancer activity of the nannocystin family of natural products has attracted significant efforts toward their total syntheses. Currently, seven total syntheses of different members of the nannocystins have been reported. In this Short Review, different synthetic approaches are highlighted. The reported structure-activity relationship (SAR) studies will also be highlighted.