Nitric Oxide and Prostacyclin are Released by Cultured Apoptotic Human Umbilical Vein Endothelial Cells Consistent with an Anti-Micro-Thrombotic Potential

Wei Xu; Emmanuel J. Favaloro; Hans Zoellner

doi:10.1055/s-0037-1613325

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 2002; 88(05): 883-884
DOI: 10.1055/s-0037-1613325

Letters to the Editor

Schattauer GmbH

Nitric Oxide and Prostacyclin are Released by Cultured Apoptotic Human Umbilical Vein Endothelial Cells Consistent with an Anti-Micro-Thrombotic Potential

Wei Xu

¹Cellular and Molecular Pathology Research Unit, Department of Oral Pathology and Oral Medicine, University of Sydney, Westmead Hospital Dental Clinical School, Westmead Hospital, Australia

,

Emmanuel J. Favaloro

²Department of Haematology, ICPMR, Westmead Hospital, Australia

,

Hans Zoellner

¹Cellular and Molecular Pathology Research Unit, Department of Oral Pathology and Oral Medicine, University of Sydney, Westmead Hospital Dental Clinical School, Westmead Hospital, Australia

References
1 Xu W, Favaloro E, Medbury H, Zoellner H. Human endothelial cells maintain anti-aggregatory activity for platelets during apoptosis. Thromb Haemost 2001; 85: 915-23.
2 Zoellner H, Hofler M, Beckmann R, Bielek E, Vanyek E, Kumabashiri I, Binder B. Fibrinolytic proteins in apoptotic human umbilical vein endothelial cells. Thromb Res 1998; 91: 209-19.
3 Zoellner H, Hofler M, Beckmann R, Hufnagl P, Vanyek E, Bielek E, Wojta J, Fabry A, Lockie S, Binder BR. Serum albumin is a specific inhibitor of apoptosis in human endothelial cells. J Cell Sci 1996; 109: 2571-80.
4 Zoellner H, Hou JY, Lovery M, Kingham J, Srivastava M, Bielek E, Vanyek E, Binder BR. Inhibition of microvascular endothelial apoptosis in tissue explants by serum albumin. Microvasc Res 1999; 57: 162-73.
5 Lai X, Liu Y, Wang J, Li S, Chen L, Guan Z. Injury to vascular endothelial cells and the change of plasma endothelin level in dogs with gunshot wounds. J Trauma Injury Infec Crit Care 1996; 40: S60-S62.
6 Meredith JJ, Fazeli B, Schwartz MA. The extracellular matrix as a cell survival factor. Mol Biol Cell 1993; 04: 953-61.
7 Zoellner H, Bielek E, Vanyek E, Fabry A, Wojta J, Hofler M, Binder B. Canalicular fragmentation of apoptotic human endothelial cells. Endothelium 1996; 04: 177-88.
8 Bombeli T, Karsan A, Tait JF, Harlan JM. Apoptotic vascular endothelial cells become procoagulant. Blood 1997; 89: 2429-42.
9 Bombeli T, Schwartz BR, Harlan JM. Endothelial cells undergoing apoptosis become proadhesive for nonactivated platelets. Blood 1999; 93: 3831-8.
10 Greeno EW, Bach RR, Moldow CF. Apoptosis is associated with increased cell surface tissue factor procoagulant activity. Lab Invest 1996; 75: 281-9.
11 Casciola-Rosen L, Rosen A, Petri M, Schlissel M. Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus. Proc Natl Acad Sci USA 1996; 93: 1624-9.