Thromb Haemost 2000; 83(03): 511
DOI: 10.1055/s-0037-1613847
Letters to the Editor
Schattauer GmbH

The C 536T Transition in the Tissue Factor Pathway Inhibitor Gene Is not a Common Cause of Venous Thromboembolic Disease in the UK Population

G. D. Evans
1   From the Addenbrookes NHS Trust, Cambridge, UK
,
J. Langdown
1   From the Addenbrookes NHS Trust, Cambridge, UK
,
K. Brown
1   From the Addenbrookes NHS Trust, Cambridge, UK
,
T. P. Baglin
1   From the Addenbrookes NHS Trust, Cambridge, UK
› Author Affiliations
Further Information

Publication History

Received 21 September 1999

Accepted 25 October 1999

Publication Date:
14 December 2017 (online)

 

 
  • References

  • 1 Broze GJ. Tissue factor pathway inhibitor gene disruption. Blood Coagulation and Fibrinolysis 1998; 09: 89-92.
  • 2 Miyata T, Sakata T, Kumeda K, Uchida K, Tsushima M, Fujimuru H, Kawasaki T, Kato H. C399-T Polymorphism in the promoter region of the Human Tissue Factor Pathway Inhibitor gene does not change the plasma TFPI antigen level and does not cause venous thrombosis. Thromb Haemost 1998; 80: 345-6.
  • 3 Arnaud E, Moatti D, Emmerich J, Aiach M, de Prost D. No link between the TFPI V264M mutation and venous thromboembolic disease. Thromb Haemost 1999; 82: 159-60.
  • 4 Kleesiek K, Schmidt M, Gotting C, Brinkman T, Prohaska W. A first mutation in the Human Tissue Factor Pathway Inhibitor gene encoding [P151L]TFPI. Blood 1998; 92: 3976-80.
  • 5 Kleesiek K, Schmidt M, Gotting C, Schwenz B, Lange S, Muller-Berghaus G, Brinkman T, Prohaska W. The 536C-T transition in the Human Tissue Factor Pathway Inhibitor gene is statistically associated with a higher risk of venous thrombosis. Thromb Haemost 1999; 82: 1-5.