Download PDF
Thromb Haemost 2004; 91(04): 636-638
DOI: 10.1055/s-0037-1614268
Editorial Focus
Schattauer GmbH

Endothelial cell microparticles and antiphospholipid syndrome: pathologic explanations and diagnostic opportunities

Ian A. Greer
1   University of Glasgow, United Kingdom
› Author Affiliations
Further Information

Publication History

Received 17 February 2004

Accepted 20 February 2004

Publication Date:
08 December 2017 (online)

Also available at
    Permissions and Reprints

 

 

  • References

  • 1 Rand JH. Molecular pathogenesis of the antiphospholipid syndrome. Circul Res 2002; 90: 29-37.
    CrossrefPubMedGoogle Scholar
  • 2 Asherson RA, Cervera R, Piette JC. et al. Catastrophic antiphospholipid syndrome: clinical and laboratory features of 50 patients. Med (Baltimore) 1998; 77: 195-207.
    CrossrefPubMedGoogle Scholar
  • 3 Shoenfeld Y, Sherer Y, Gorge J. et al. Autoantibodies associated with atherosclerosis. Ann Med 2000; 32: 37-40.
    PubMedGoogle Scholar
  • 4 Meroni PL, Riboldi P. Pathogenic mechanisms mediating antiphospholipid syndrome. Curr Opin Rheumatol 2001; 113: 37-82.
    PubMedGoogle Scholar
  • 5 Galli M, Grassi I, Barbui T. Platelet-derived microvesicles in thrombotic thrombocytopenic purpura and haemolytic uremic syndrome. Thromb Haemost 1996; 75: 427-31.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 6 Mallat Z, Benamer H. Hugel et al. Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes. Circulation 2000; 101: 841-8.
    CrossrefPubMedGoogle Scholar
  • 7 Gilbert GE, Sims PJ, Widemer T. et al. Platelet-derived microparticles express higher affinity receptors for Factor VIII. J Biol Chem 1999; 266: 17261-8.
    PubMedGoogle Scholar
  • 8 Barry OP, Practico D, Lawson JA. et al. Transfer of activation of platelets and endothelial cells by bioactive lipids and platelet microparticles. J Clin Invest 1997; 90: 2118-27.
    PubMedGoogle Scholar
  • 9 Albanese J, Meterissian S, Kontogiannea M. et al. Biologically active FAS antigen and its cognate ligand or expressed and plasma membrane derived extracellular vesicles. Blood 1998; 91: 3862-74.
    PubMedGoogle Scholar
  • 10 Messri M, Altieri DC. Endothelial cell activation by leukocyte microparticles. J Immunol 1998; 161: 4382-7.
    PubMedGoogle Scholar
  • 11 Dignat-George et al. Endothelial microparticles: a potential contribution to the thrombotic complications of the antiphospholid syndrome. Thomb Haemost 2004; 91: 667-73.
    PubMedGoogle Scholar
  • 12 Combes B, Simon AC, Grau GE. et al. In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant. J Clin Invest 1999; 104: 93-102.
    CrossrefPubMedGoogle Scholar
  • 13 Galli M. Which antiphospholipid antibodies should be measured in the antiphospholipid syndrome?. Haemostasis 2000; 30 (Suppl. 02) 57-62.
    PubMedGoogle Scholar
  • 14 Beutler B, Bazzoni F. TNF apoptosis and autoimmunity a common thread?. Blood Cells Mol Dis 1998; 24: 216-30.
    CrossrefPubMedGoogle Scholar