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Thromb Haemost 1999; 81(01): 162-163
DOI: 10.1055/s-0037-1614436
DOI: 10.1055/s-0037-1614436
Letters to the Editor
Simultaneous Genotyping for Factor V Leiden and Prothrombin G20210A Variant by a Multiplex PCR-SSCP Assay on Whole Blood
Further Information
Publication History
Received07 August 1998
Accepted after revision22 September 1998
Publication Date:
08 December 2017 (online)
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References
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- 2 Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3’-untranslated region of the PT gene is associated with elevated plasma prothrombin levels and in an increase in venous thrombosis. Blood 1996; 88: 3698-703.
- 3 Ripoll L, Paulin D, Thomas S, Drouet LO. Multiplex PCR-mediated site-directed mutagenesis for one-step determination of factor V Leiden and G20210A transition of the prothrombin gene. Thromb Haemost 1997; 90: 960-1.
- 4 Gómez E, van der Poel SCPAM, Jansen J, van der Reijden BA, Leuwenberg B. Rapid simultaneous screening of factor V leiden and G20210A prothrom-bin variant by multiplex polymerase chain reaction on whole blood. Blood 1998; 91: 2208-9.
- 5 Bowen DJ, Bowley S, John M, Collins PW. Factor V Leiden (G1691A), the prothrombin 3’-untranslated region variant (G20210A) and thermolabile methylenetetrahydrofolate reductase (C677T): A single genetic test genotypes all three loci - determination of frequencies in the S. Wales population of the UK. Thromb Haemost 1998; 79: 949-54.
- 6 Hézard N, Cornillet-Lefebvre P, Gillot L, Potron G, Nguyen P. Multiplex ASA PCR for a simultaneous determination of factor V Leiden gene, G A 20210 prothrombin gene and C T 677 MTHFR gene mutations. Thromb Haemost 1998; 79: 1054-5.