Inventory of Exogenous Hemostatic Factors Derived from Arthropods

C. L. Arocha-Piñango; R. Marchi; B. Guerrero

doi:10.1055/s-0037-1614540

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 1999; 81(04): 647-656
DOI: 10.1055/s-0037-1614540

Scientific and Standardization Committee Communication

Schattauer GmbH

Inventory of Exogenous Hemostatic Factors Derived from Arthropods

On behalf of the Registry of Exogenous Hemostatic Factors of the Scientific and Standardization Subcommittee of the International Society on Thrombosis and Haemostasis; Registry Chairman: Neville Marsh

C. L. Arocha-Piñango

¹From the Instituto Venezolano de Investigaciones Científicas (IVIC), Centro de Medicina Experimental, Caracas, Venezuela

,

R. Marchi

¹From the Instituto Venezolano de Investigaciones Científicas (IVIC), Centro de Medicina Experimental, Caracas, Venezuela

,

B. Guerrero

¹From the Instituto Venezolano de Investigaciones Científicas (IVIC), Centro de Medicina Experimental, Caracas, Venezuela

› Institutsangaben

Abstract

Summary

In many arthropods agents have been detected which affect the hemostatic mechanism. Some agents, such as those identified in hematophagus arthropods, seem to have evolved to help the animal in the feeding process while, in others, the function cannot be explained, but may be part of a defense mechanism (see Refs. 1-3).

Some arthropods possess several agents while in others one agent has different activities, i.e., antithrombin activity as well as inhibition of platelet aggregation. Many agents have been only partially characterized while others have been cloned and prepared in recombinant form.The majority of the agents are small proteins. As to the nomenclature, some agents have been described by the authors but have not been assigned proper names.

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Referenzen

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