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Thromb Haemost 1998; 79(04): 741-742
DOI: 10.1055/s-0037-1615056
Rapid Communication
Schattauer GmbH

Superficial Vein Thrombosis: Incidence in Association with Pregnancy and Prevalence of Thrombophilic Defects

M. D. McColl
1   From the Dept. of Haematology, Royal Infirmary, Glasgow, UK.
,
J. E. Ramsay
2   From the Glasgow Royal Maternity Hospital, Glasgow, UK
,
R. C. Tait
3   From the Southern General NHS Trust, Glasgow, UK
,
I. D. Walker
1   From the Dept. of Haematology, Royal Infirmary, Glasgow, UK.
,
F. McCall
1   From the Dept. of Haematology, Royal Infirmary, Glasgow, UK.
,
J. A. Conkie
1   From the Dept. of Haematology, Royal Infirmary, Glasgow, UK.
,
M. J. Carty
3   From the Southern General NHS Trust, Glasgow, UK
,
I. A. Greer
2   From the Glasgow Royal Maternity Hospital, Glasgow, UK
› Author Affiliations
Further Information

Publication History

Received 12 September 1997

Accepted after revision 26 November 1997

Publication Date:
07 December 2017 (online)

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Summary

Superficial venous thrombotic (SVT) events are a feature of thrombophilic abnormalities, particularly those involving the protein C pathway. We have determined the incidence of SVT associated with pregnancy and the early postpartum period in a retrospective study involving 72 000 deliveries. Fourty-nine cases occurring in 47 individuals were recorded, with an overall incidence of 0.68/1000 deliveries (95% CI 0.48-0.88). None had a previous history of deep vein thrombosis or pulmonary embolism. Most events occurred in the early post-partum period (0.54/1000 deliveries). Twenty-four/fourty-seven were screened for established thrombophilic abnormalities, with only 1 abnormality detected (FVLeiden heterozygote). Thrombophilia may play a minor role in the aetiology of SVT associated with pregnancy, although a larger study is required to confirm this.

 

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