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Thromb Haemost 1998; 79(05): 1054-1055
DOI: 10.1055/s-0037-1615119
DOI: 10.1055/s-0037-1615119
Letters to the Editor
Multiplex ASA PCR for a Simultaneous Determination of Factor V Leiden Gene, G → A 20210 Prothrombin Gene and C → T677 MTHFR Gene Mutations
Further Information
Publication History
Received
10 October 1997
Accepted after revision
16 January 1998
Publication Date:
07 December 2017 (online)
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References
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- 2 Bertina RM, Koeleman BPC, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-7.
- 3 Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3’-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-703.
- 4 Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJH, den Heijer M, Kluijtmans LAJ, van den Heuvel LP, Rozen R. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nature Genetics 1995; 10: 111-3.
- 5 Hézard N, Cornillet P, Droullé C, Gillot L, Potron G, Nguyen P. Factor V Leiden: detection in whole blood by ASA PCR using an additional mismatch in antepenultimate position. Thromb Res 1997; 88: 59-66.
- 6 Poort SR, Bertina RM, Vos HL. Rapid detection of the prothrombin 20210A variation by allele specific PCR. Thromb Haemost 1997; 78: 1157-8.
- 7 Seligsohn U, Zivelin A. Thrombophilia as a multigenic disorder. Thromb Haemost 1997; 78: 297-301.