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Thromb Haemost 2001; 85(02): 207-217
DOI: 10.1055/s-0037-1615678
Review Article
Schattauer GmbH

An Update of the Grützbalgϕ Hypothesis: The Role of Thrombosis and Coagulation in Atherosclerotic Progression

Karen O. Yee
1   Department of Pathology, University of Washington, Seattle, Washington, USA
,
Yuji Ikari
1   Department of Pathology, University of Washington, Seattle, Washington, USA
,
Stephen M. Schwartz
1   Department of Pathology, University of Washington, Seattle, Washington, USA
› Author Affiliations
Further Information

Publication History

Received 11 May 2000

Accepted after revision 27 July 2000

Publication Date:
08 December 2017 (online)

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Summary

While a great deal has been learned about the initiation of atherosclerosis, much less is known about the factors that ultimately determine progression and clinical manifestations. In this review we will focus on the possible role of coagulation, especially intramural fibrin in lesion progression.

Keywords

Atherosclerosis - plaque rupture - coagulation - remodelling
 

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