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Thromb Haemost 2001; 85(05): 943-944
DOI: 10.1055/s-0037-1615777
Letters to the Editor
Schattauer GmbH

A Novel Point Mutation in the 3’ Region of the Prothrombin Gene at Position 20221 in a Lebanese/Syrian Family

Mark Wylenzek  
1   Institut für Klinische Chemie, Universität zu Köln, Köln, Germany
,
Christof Geisen  
1   Institut für Klinische Chemie, Universität zu Köln, Köln, Germany
,
Ludwig Stapenhorst
2   Klinik und Poliklinik für Allgemeine Kinderheilkunde, Universität zu Köln, Köln, Germany
,
Klaus Wielckens
1   Institut für Klinische Chemie, Universität zu Köln, Köln, Germany
,
Karl R. Klingler
1   Institut für Klinische Chemie, Universität zu Köln, Köln, Germany
› Author Affiliations
Further Information

Publication History

Received 28 December 2001

Accepted after resubmission 08 January 2001

Publication Date:
11 December 2017 (online)

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M. W. and C. G. both contributed equally to this letter


 

  • References

  • 1 Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-703.
    PubMedGoogle Scholar
  • 2 Oh J, Schaefer F, Veldmann A, Nowak G, Nowak-Gottl U, Tonshoff B, Kreuz W. Heterozygous prothrombin gene mutation: a new risk factor for early renal allograft thrombosis. Transplantation 1999; 68: 575-8.
    CrossrefPubMedGoogle Scholar